SCHEMBL120092

SCHEMBL120092

Fc1cc(F)cc(CBr)c1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.46
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
TRPA1 O75762 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
DAO P14920 2/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
DBH P09172 1/20 0.33
TAAR1 Q96RJ0 1/20 0.31
AGXT P21549 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5487052 1.00 IDO1 (0.46) IDO1CA12CA1CA9TRPA1
SCHEMBL5733912 1.00 IDO1 (0.46) IDO1CA12CA1CA9TRPA1
SCHEMBL11029571 0.97 IDO1 (0.44) IDO1CA12CA1CA9TRPA1
Pentane SCHEMBL28136158 0.85 IDO1 (0.37) IDO1TSHR
SCHEMBL29472374 0.84 IDO1 (0.34) IDO1TRPA1ALDH1A1TSHR
SCHEMBL671058 0.84 IDO1 (0.34) IDO1TRPA1ALDH1A1TSHR
SCHEMBL25077209 0.82 IDO1 (0.38) IDO1TAAR1
SCHEMBL2924850 0.82 ACHE (0.36) IDO1
SCHEMBL857310 0.82 DAO (0.37) IDO1TSHRDAO
SCHEMBL20503990 0.82 IDO1 (0.33) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954778-A Synthesis method of lenacipam sodium and series of intermediate compounds thereof 杭州科巢生物科技有限公司 2025-05-09 CN claimed
CN-119031729-A Perovskite solar cell for regulating perovskite crystallization by 3, 5-difluorobenzyl bromide, perovskite-based laminated solar cell and preparation method 中国长江三峡集团有限公司 2024-11-26 CN claimed
CN-115785080-B Uracil parent nucleus compound and preparation method and application thereof 陕西盘龙药业集团股份有限公司 2024-10-11 CN claimed
CN-118063504-A Fluoro phenyl phosphate compound, perovskite thin film, perovskite solar cell, preparation method, electric equipment and application 天合光能股份有限公司 2024-05-24 CN claimed
CN-115232126-B Beta-carbolin-1, 2, 3-triazole compound, preparation method thereof and application of compound in resisting Alzheimer disease 中国人民解放军北部战区总医院 2023-04-25 CN claimed
CN-115232126-A Beta-carbopol-1, 2, 3-triazole compound, preparation method thereof and application thereof in resisting Alzheimer disease 中国人民解放军北部战区总医院 2022-10-25 CN claimed
EP-3752496-A1 METHODS AND INTERMEDIATES FOR PREPARING A THERAPEUTIC COMPOUND USEFUL IN THE TREATMENT OF RETROVIRIDAE VIRAL INFECTION GILEAD SCIENCES, INC. (US) 2020-12-23 EP claimed
CN-112055712-A Processes and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections 吉利德科学公司 2020-12-08 CN claimed
WO-2019161280-A1 METHODS AND INTERMEDIATES FOR PREPARING A THERAPEUTIC COMPOUND USEFUL IN THE TREATMENT OF RETROVIRIDAE VIRAL INFECTION GILEAD SCIENCES, INC. (US) 2019-08-22 WO claimed
EP-1622907-A1 AZABICYCLONONENE DERIVATIVES Actelion Pharmaceuticals Ltd. (CH) 2006-02-08 EP claimed
WO-2004096803-A1 AZABICYCLONONENE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2004-11-11 WO claimed
CN-116854630-B Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections 吉利德科学公司 2026-05-19 CN disclosed
EP-4737448-A1 SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF Artivila (ShenZhen) Innovation Center, Ltd. (CN) 2026-05-06 EP disclosed
EP-4736882-A2 TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE Cullgen (Shanghai), Inc. (CN) 2026-05-06 EP disclosed
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 US disclosed
US-5387593-A Anxiolytic agents BRISTON-MYERS SQUIBB (US) 1995-02-07 US disclosed
US-5380729-A Treatment or prevention of neurodegenerative disorders or neurotoxic injuries STERLING WINTHROP INC. (US) 1995-01-10 US disclosed
EP-0629604-A2 Alicyclic phospholipase A2 inhibitors Bristol-Myers Company (US) 1994-12-21 EP disclosed
WO-1994024130-A1 NEW PYRIDINIUM SALTS AND THEIR USE FOR CONTROLLING HELICOBACTER BACTERIA BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1994-10-27 WO disclosed
EP-0546583-A1 Piperazinyl-and piperidinyl-cyclohexanols Bristol-Myers Squibb Company (US) 1993-06-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570675-B2 Boronic acid compounds PSMB6, PSMB3, PSMB2 IDO1 3016/4885CA12 381/4885CA1 477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.