Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | DBH | P09172 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | AGXT | P21549 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120092 | 1.00 | IDO1 (0.46) | IDO1CA12CA1CA9TRPA1 | |
| SCHEMBL5733912 | 1.00 | IDO1 (0.46) | IDO1CA12CA1CA9TRPA1 | |
| SCHEMBL11029571 | 0.97 | IDO1 (0.44) | IDO1CA12CA1CA9TRPA1 | |
| Pentane SCHEMBL28136158 | 0.85 | IDO1 (0.37) | IDO1TSHR | |
| SCHEMBL29472374 | 0.84 | IDO1 (0.34) | IDO1TRPA1ALDH1A1TSHR | |
| SCHEMBL671058 | 0.84 | IDO1 (0.34) | IDO1TRPA1ALDH1A1TSHR | |
| SCHEMBL25077209 | 0.82 | IDO1 (0.38) | IDO1TAAR1 | |
| SCHEMBL2924850 | 0.82 | ACHE (0.36) | IDO1 | |
| SCHEMBL857310 | 0.82 | DAO (0.37) | IDO1TSHRDAO | |
| SCHEMBL20503990 | 0.82 | IDO1 (0.33) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105921-A1 | Process for Preparing Oxazole Intermediates | PHARMACIA & UPJOHN COMPANY | 2007-05-10 | — | — | US | disclosed |
| US-7115747-B2 | Process for preparing oxazole intermediates | PHARMACIA & UPJOHN COMPANY (US) | 2006-10-03 | — | — | US | disclosed |
| EP-1532123-A1 | PROCESS FOR PREPARING 5-(1, 3-OXAZOL-2-YL) BENZOIC ACID DERIVATIVES | Pharmacia & Upjohn Company LLC (US) | 2005-05-25 | — | — | EP | disclosed |
| US-20040063965-A1 | Process for preparing oxazole intermediates | PHARMACEIA & UPJOHN | 2004-04-01 | — | — | US | disclosed |
| WO-2004000821-A1 | PROCESS FOR PREPARING 5-(1, 3-OXAZOL-2-YL) BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063965-A1 | Process for preparing oxazole intermediates | PSEN1, SOD1, OXA1L | IDO1 1076/4885CA12 1968/4885CA1 126/4885 |
| US-20070105921-A1 | Process for Preparing Oxazole Intermediates | OXA1L, SOD1, PSEN1 | IDO1 1363/4885CA12 2238/4885CA1 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.