Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12011503 | 0.86 | GSTP1 (0.37) | CYP11B2CYP1A2CYP11B1CYP3A4CYP2D6 | |
| SCHEMBL11367640 | 0.82 | ACACA (0.48) | CYP11B2CYP1A2CYP11B1CYP3A4CYP2D6 | |
| SCHEMBL12253343 | 0.81 | CYP1A2 (0.47) | CYP11B2CYP1A2CYP11B1CYP3A4CYP2D6 | |
| SCHEMBL22993026 | 0.79 | CYP1A2 (0.57) | CYP11B2CYP1A2CYP11B1CYP3A4CYP2D6 | |
| SCHEMBL1041430 | 0.79 | CYP1A2 (0.61) | CYP11B2CYP1A2CYP11B1CYP3A4CYP2D6 | |
| SCHEMBL12011498 | 0.79 | IKBKB (0.34) | CYP11B2CYP1A2CYP11B1CYP3A4CYP2D6 | |
| SCHEMBL12011499 | 0.79 | IKBKB (0.34) | CYP11B2CYP1A2CYP11B1CYP3A4CYP2D6 | |
| SCHEMBL13147454 | 0.78 | CYP1A2 (0.46) | CYP11B2CYP1A2CYP11B1CYP3A4CYP2D6 | |
| SCHEMBL12011506 | 0.78 | LMNA (0.34) | CYP1A2CYP2D6CYP2C9CYP2C19KDM4E | |
| SCHEMBL11978883 | 0.77 | CYP11B2 (0.56) | CYP11B2CYP1A2CYP11B1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8253129-B2 | Benzochrysene derivative and an organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-08-28 | — | — | US | disclosed |
| US-8253129-B2 | Benzochrysene derivative and an organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-08-28 | — | — | US | disclosed |
| US-20100295029-A1 | BENZOCHRYSENE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. | 2010-11-25 | — | — | US | disclosed |
| US-20100295029-A1 | BENZOCHRYSENE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100295029-A1 | BENZOCHRYSENE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | KSR1, NRAS, RSU1 | CYP11B2 4131/4885CYP1A2 3166/4885CYP11B1 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.