SCHEMBL1201247

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3155966	0.79	ALDH1A1 (0.60)	KMT2AMEN1ALDH1A1CA1CA2
	SCHEMBL7896686	0.74	KMT2A (0.68)	KMT2AMEN1ALDH1A1CA1CA2
	SCHEMBL12751034	0.73	KMT2A (0.66)	KMT2AMEN1ACHEALDH1A1CA1
	SCHEMBL7058489	0.72	KMT2A (0.59)	KMT2AMEN1ALDH1A1CA1CA2
	2-Nitrobenzaldehyde SCHEMBL29672618	0.72	ERN1 (0.66)	KMT2AMEN1ERN1ALDH1A1GAA
	2-Nitrobenzaldehyde SCHEMBL5654	0.72	ERN1 (0.66)	KMT2AMEN1ERN1ALDH1A1GAA
	SCHEMBL1199797	0.72	ALDH1A1 (0.46)	KMT2AMEN1ALDH1A1MAPK1SMN1; SMN2
	SCHEMBL9948638	0.72	KMT2A (0.63)	KMT2AMEN1ALDH1A1CA1CA2
	SCHEMBL14613962	0.72	KMT2A (0.63)	KMT2AMEN1ALDH1A1CA1CA2
	SCHEMBL11260836	0.72	KMT2A (0.63)	KMT2AMEN1ALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.