Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 2/20 | 0.38 |
| ▸ | PGK2 | P07205 | 2/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13541165 | 0.83 | CA2 (0.48) | PGK1PGK2ESR1ESR2CA2 | |
| SCHEMBL12012729 | 0.79 | POLB (0.43) | PGK1PGK2SHBGESR1ESR2 | |
| SCHEMBL1021767 | 0.73 | ALDH1A1 (0.48) | SHBGESR1ESR2GABRA1GABRB2 | |
| SCHEMBL31028130 | 0.73 | CA1 (0.59) | SHBGESR1ESR2GABRA1GABRB2 | |
| SCHEMBL30576381 | 0.73 | ALDH1A1 (0.48) | SHBGESR1ESR2GABRA1GABRB2 | |
| SCHEMBL30250589 | 0.73 | CA1 (0.59) | SHBGESR1ESR2GABRA1GABRB2 | |
| SCHEMBL9749694 | 0.73 | CA1 (0.59) | SHBGESR1ESR2GABRA1GABRB2 | |
| SCHEMBL70083 | 0.73 | CYP3A4 (0.42) | SHBGESR1ESR2GABRA1GABRB2 | |
| SCHEMBL27647441 | 0.72 | ESR1 (0.44) | SHBGESR1ESR2GABRA1GABRB2 | |
| SCHEMBL1022721 | 0.71 | SHBG (0.55) | SHBGESR1ESR2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252954-B2 | Processes for the preparation of calixarene derivatives | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2012-08-28 | — | — | US | disclosed |
| US-20100185022-A1 | PROCESSES FOR THE PREPARATION OF CALIXARENE DERIVATIVES | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100185022-A1 | PROCESSES FOR THE PREPARATION OF CALIXARENE DERIVATIVES | CALD1, CANX, CALU | PGK1 776/4885PGK2 866/4885SHBG 3044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.