SCHEMBL1201503

SCHEMBL1201503

OCc1cc(F)c(F)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.33
CES1 P23141 2/20 0.33
HDAC3 O15379 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA4 P22748 2/20 0.31
GRIA1 P42261 1/20 0.30
GRIA2 P42262 1/20 0.30
GRIA3 P42263 1/20 0.30
GRIA4 P48058 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28271940 0.85
SCHEMBL6317338 0.80 HDAC3 (0.31) CES2CES1HDAC3HDAC6CA2
SCHEMBL522761 0.80 CBFB (0.33)
SCHEMBL13068538 0.80 CES2 (0.31) CES2CES1
SCHEMBL2965654 0.79 CES2 (0.33) CES2CES1HDAC3HDAC6CA1
SCHEMBL13082893 0.78 PTPN1 (0.32) CES2CES1
SCHEMBL9819114 0.78 PDK2 (0.33)
SCHEMBL8724892 0.78 PDK2 (0.30) CES2CES1
SCHEMBL30267640 0.77 GRIA1 (0.40) CES2CES1CA2CA4GRIA1
SCHEMBL650981 0.77 GRIA1 (0.40) CES2CES1CA2CA4GRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-217663367-U Tetrafluorobenzyl alcohol automatic reduction reaction equipment 福建润华化工有限公司 2022-10-28 CN claimed
CN-109293478-B Method for preparing tetrafluorobenzyl alcohol 大连奇凯医药科技有限公司 2021-08-06 CN claimed
CN-213724956-U Tetrafluorobenzyl alcohol continuous extraction equipment 福建润华化工有限公司 2021-07-20 CN claimed
CN-213726516-U Tetrafluorobenzyl alcohol intelligent reduction reaction device 福建润华化工有限公司 2021-07-20 CN claimed
CN-111362962-A Tetrafluorobenzyl norcantharidin carboxylate and synthesis method thereof 遵义医科大学 2020-07-03 CN claimed
CN-109810572-A Inorganic nano material prints ink and its preparation method and application 深圳TCL工业研究院有限公司 2019-05-28 CN claimed
CN-109293478-A A method of preparing tetrafluorobenzyl alcohol 大连奇凯医药科技有限公司 2019-02-01 CN claimed
CN-105777495-A Tetrafluorobenzyl alcohol producing mechanical device 江苏维尤纳特精细化工有限公司 2016-07-20 CN claimed
CN-204385102-U Novel tetrafluorobenzyl alcohol production equipment JIANGSU WEUNITE FINE CHEM CO LTD 2015-06-10 CN claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
CN-101323571-A Pyrethroid compounds, preparation and use thereof JIANGSU YANGNONG CHEMICAL GROU (CN) 2008-12-17 CN claimed
EP-1975147-A1 TETRAFLUOROTOLUENE COMPOUND, METHOD FOR PRODUCING SAME AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2008-10-01 EP claimed
US-20080167492-A1 Process of Preparation of Substituted Tetrafluorobenzylaniline Compound and Its Pharmaceutically Approved Salts CHOONGWAE PHARMA CORPORATION (KR) 2008-07-10 US claimed
CN-101180263-A Process for preparing substituted tetrafluorobenzylaniline compounds and pharmaceutically acceptable salts thereof CHOONGWAE PHARMA CORP (KR) 2008-05-14 CN claimed
EP-1883619-A1 PROCESS OF PREPARATION OF SUBSTITUTED TETRAFLUOROBENZYLANILINE COMPOUND AND ITS PHARMACEUTICALLY APPROVED SALTS Choongwae Pharma Corporation (KR) 2008-02-06 EP claimed
EP-1182184-B1 PROCESS FOR PRODUCING TETRAFLUORO BENZENECARBALDEHYDES AND TETRAFLUORO BENZENEMETHANOLS SHOWA DENKO KK (JP) 2007-04-18 EP claimed
WO-2006126846-A1 PROCESS OF PREPARATION OF SUBSTITUTED TETRAFLUOROBENZYLANILINE COMPOUND AND ITS PHARMACEUTICALLY APPROVED SALTS CHOONGWAE PHARMA CORPORATION (KR) 2006-11-30 WO claimed
US-6624336-B1 Acetalization of tetrafluorobenzonitriles using alcohols, in the presence of mineral acids and metal catalysts to form chemical intermediates for nontoxic insecticides SHOWA DENKO K.K. (JP) 2003-09-23 US claimed
CN-1349484-A Process for producing tetrafluorobenzyl alcohol SHOWA DENKO KK (JP) 2002-05-15 CN claimed
EP-1182184-A1 PROCESS FOR PRODUCING TETRAFLUORO BENZENEMETHANOLS Showa Denko K K (JP) 2002-02-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080167492-A1 Process of Preparation of Substituted Tetrafluorobenzylaniline Compound and Its Pharmaceutically Approved Salts IL5, CYP3A5, PGA5 CES2 3381/4885CES1 4330/4885HDAC3 3944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.