Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29261708 | 0.92 | CES2 (0.36) | CES2CES1BCHEHSD11B1KCNN4 | |
| Fluorobenzene SCHEMBL19873496 | 0.90 | KCNN4 (0.39) | CES2CES1BCHEHSD11B1KCNN4 | |
| SCHEMBL24901415 | 0.82 | MEN1 (0.39) | CES2CES1BCHEHSD11B1PDK2 | |
| SCHEMBL2965656 | 0.81 | CES2 (0.41) | CES2CES1BCHEHSD11B1KCNN4 | |
| SCHEMBL448487 | 0.80 | HSD11B1 (0.47) | CES2CES1BCHEHSD11B1PTGS2 | |
| SCHEMBL29551965 | 0.80 | HSD11B1 (0.47) | CES2CES1BCHEHSD11B1PTGS2 | |
| SCHEMBL7777113 | 0.80 | KCNN4 (0.44) | CES2CES1KCNN4PDK2PDK1 | |
| SCHEMBL19225364 | 0.79 | CES2 (0.40) | CES2CES1BCHEHSD11B1KCNN4 | |
| SCHEMBL19135684 | 0.79 | CES2 (0.40) | CES2CES1BCHEHSD11B1KCNN4 | |
| SCHEMBL1201613 | 0.78 | CES2 (0.39) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-217663367-U | Tetrafluorobenzyl alcohol automatic reduction reaction equipment | 福建润华化工有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-109293478-B | Method for preparing tetrafluorobenzyl alcohol | 大连奇凯医药科技有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-213726516-U | Tetrafluorobenzyl alcohol intelligent reduction reaction device | 福建润华化工有限公司 | 2021-07-20 | — | — | CN | claimed |
| CN-213724956-U | Tetrafluorobenzyl alcohol continuous extraction equipment | 福建润华化工有限公司 | 2021-07-20 | — | — | CN | claimed |
| CN-111362962-A | Tetrafluorobenzyl norcantharidin carboxylate and synthesis method thereof | 遵义医科大学 | 2020-07-03 | — | — | CN | claimed |
| CN-109293478-A | A method of preparing tetrafluorobenzyl alcohol | 大连奇凯医药科技有限公司 | 2019-02-01 | — | — | CN | claimed |
| CN-105777495-A | Tetrafluorobenzyl alcohol producing mechanical device | 江苏维尤纳特精细化工有限公司 | 2016-07-20 | — | — | CN | claimed |
| CN-204385102-U | Novel tetrafluorobenzyl alcohol production equipment | JIANGSU WEUNITE FINE CHEM CO LTD | 2015-06-10 | — | — | CN | claimed |
| CN-101346334-B | Tetrafluorotoluene compound, method for producing same and use thereof | SUMITOMO CO LTD | 2013-04-24 | — | — | CN | claimed |
| EP-1883619-B1 | PROCESS OF PREPARATION OF SUBSTITUTED TETRAFLUOROBENZYLANILINE COMPOUND AND ITS PHARMACEUTICALLY APPROVED SALTS | CHOONGWAE PHARMA CORP (KR) | 2013-03-20 | — | — | EP | claimed |
| US-7495126-B2 | Process of preparation of substituted tetrafluorobenzylaniline compound and its pharmaceutically approved salts | CHOONGWAE PHARMA CORPORATION (KR) | 2009-02-24 | — | — | US | claimed |
| CN-101348437-A | Pyrethroid compounds, preparation and use thereof | JIANGSU YANGNONG CHEMICAL GROU (CN) | 2009-01-21 | — | — | CN | claimed |
| CN-101346334-A | Tetrafluorotoluene compound, method for producing same and use thereof | SUMITOMO CHEMICAL CO (JP) | 2009-01-14 | — | — | CN | claimed |
| CN-101323571-A | Pyrethroid compounds, preparation and use thereof | JIANGSU YANGNONG CHEMICAL GROU (CN) | 2008-12-17 | — | — | CN | claimed |
| EP-1975147-A1 | TETRAFLUOROTOLUENE COMPOUND, METHOD FOR PRODUCING SAME AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-10-01 | — | — | EP | claimed |
| US-20080167492-A1 | Process of Preparation of Substituted Tetrafluorobenzylaniline Compound and Its Pharmaceutically Approved Salts | CHOONGWAE PHARMA CORPORATION (KR) | 2008-07-10 | — | — | US | claimed |
| CN-101180263-A | Process for preparing substituted tetrafluorobenzylaniline compounds and pharmaceutically acceptable salts thereof | CHOONGWAE PHARMA CORP (KR) | 2008-05-14 | — | — | CN | claimed |
| EP-1883619-A1 | PROCESS OF PREPARATION OF SUBSTITUTED TETRAFLUOROBENZYLANILINE COMPOUND AND ITS PHARMACEUTICALLY APPROVED SALTS | Choongwae Pharma Corporation (KR) | 2008-02-06 | — | — | EP | claimed |
| WO-2006126846-A1 | PROCESS OF PREPARATION OF SUBSTITUTED TETRAFLUOROBENZYLANILINE COMPOUND AND ITS PHARMACEUTICALLY APPROVED SALTS | CHOONGWAE PHARMA CORPORATION (KR) | 2006-11-30 | — | — | WO | claimed |
| CN-1349484-A | Process for producing tetrafluorobenzyl alcohol | SHOWA DENKO KK (JP) | 2002-05-15 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167492-A1 | Process of Preparation of Substituted Tetrafluorobenzylaniline Compound and Its Pharmaceutically Approved Salts | IL5, CYP3A5, PGA5 | CES2 3381/4885CES1 4330/4885BCHE 2506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.