Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1202751 | 0.85 | KMT2A (0.43) | KMT2AMAPTLMNACYP2C19CYP1A2 | |
| SCHEMBL609760 | 0.73 | CYP19A1 (0.36) | — | |
| SCHEMBL6099839 | 0.71 | THRB (0.32) | SLC6A3 | |
| SCHEMBL14236682 | 0.67 | KMT2A (0.45) | KMT2AMAPTHPGDLMNACYP2D6 | |
| SCHEMBL1969939 | 0.66 | L3MBTL1 (0.57) | MAPTHPGDLMNACYP2D6CYP2C19 | |
| SCHEMBL610755 | 0.65 | KMT2A (0.69) | KMT2AMAPTHPGDCYP1A2CYP2C9 | |
| SCHEMBL28003430 | 0.65 | KMT2A (0.69) | KMT2AMAPTHPGDCYP1A2CYP2C9 | |
| SCHEMBL10599787 | 0.65 | KMT2A (0.69) | KMT2AMAPTHPGDCYP1A2CYP2C9 | |
| SCHEMBL9683516 | 0.65 | KMT2A (0.69) | KMT2AMAPTHPGDCYP1A2CYP2C9 | |
| SCHEMBL607707 | 0.63 | MAOA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756059-B1 | PROCESS FOR THE PRODUCTION OF CYCLIC DIKETONES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-07 | — | — | EP | disclosed |
| EP-1756059-B1 | PROCESS FOR THE PRODUCTION OF CYCLIC DIKETONES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-07 | — | — | EP | disclosed |
| EP-1740524-B1 | PROCESS FOR THE PRODUCTION OF CYCLIC DIKETONES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-12-12 | — | — | EP | disclosed |
| US-7893270-B2 | Reacting 2,4,4-tribromobicyclo[3.2.1]oct-2-ene in chlorobenzene with acetonitrile and sulfuric acid to produce 4-bromo-bicyclo[3.2.1]oct-3-en-2-one | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-7893270-B2 | Reacting 2,4,4-tribromobicyclo[3.2.1]oct-2-ene in chlorobenzene with acetonitrile and sulfuric acid to produce 4-bromo-bicyclo[3.2.1]oct-3-en-2-one | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-7893270-B2 | Reacting 2,4,4-tribromobicyclo[3.2.1]oct-2-ene in chlorobenzene with acetonitrile and sulfuric acid to produce 4-bromo-bicyclo[3.2.1]oct-3-en-2-one | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-7501544-B2 | Process for the production of cyclic diketones | SYNGENTA CROP PROTECTION, INC. (US) | 2009-03-10 | — | — | US | disclosed |
| US-7501544-B2 | Process for the production of cyclic diketones | SYNGENTA CROP PROTECTION, INC. (US) | 2009-03-10 | — | — | US | disclosed |
| US-7501544-B2 | Process for the production of cyclic diketones | SYNGENTA CROP PROTECTION, INC. (US) | 2009-03-10 | — | — | US | disclosed |
| US-20080139816-A1 | Process For the Production of Cyclic Diketones | SYNGENTA CROP PROTECTION, INC. (US) | 2008-06-12 | — | — | US | disclosed |
| US-20080139816-A1 | Process For the Production of Cyclic Diketones | SYNGENTA CROP PROTECTION, INC. (US) | 2008-06-12 | — | — | US | disclosed |
| US-20080139816-A1 | Process For the Production of Cyclic Diketones | SYNGENTA CROP PROTECTION, INC. (US) | 2008-06-12 | — | — | US | disclosed |
| US-20070232837-A1 | Process for the Production of Cyclic Diketones | SYNGENTA CROP PROTECTION, INC. (US) | 2007-10-04 | — | — | US | disclosed |
| US-20070232837-A1 | Process for the Production of Cyclic Diketones | SYNGENTA CROP PROTECTION, INC. (US) | 2007-10-04 | — | — | US | disclosed |
| US-20070232837-A1 | Process for the Production of Cyclic Diketones | SYNGENTA CROP PROTECTION, INC. (US) | 2007-10-04 | — | — | US | disclosed |
| EP-1756059-A1 | PROCESS FOR THE PRODUCTION OF CYCLIC DIKETONES | Syngeta Participations AG (CH) | 2007-02-28 | — | — | EP | disclosed |
| EP-1740524-A2 | PROCESS FOR THE PRODUCTION OF CYCLIC DIKETONES | Syngeta Participations AG (CH) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105718-A2 | PROCESS FOR THE PRODUCTION OF CYCLIC DIKETONES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-11-10 | — | — | WO | disclosed |
| WO-2005105745-A1 | PROCESS FOR THE PRODUCTION OF CYCLIC DIKETONES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232837-A1 | Process for the Production of Cyclic Diketones | CA9, ACAD9, F9 | KMT2A 3019/4885MAPT 4489/4885HPGD 3033/4885 |
| US-20080139816-A1 | Process For the Production of Cyclic Diketones | BCKDK, KCNJ1, KCNJ11 | KMT2A 1751/4885MAPT 3792/4885HPGD 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.