Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18801610 | 0.85 | — | — | |
| SCHEMBL11922034 | 0.85 | RXRA (0.50) | RXRARXRBNPC1RAB9AL3MBTL1 | |
| SCHEMBL12018578 | 0.84 | KDM4E (0.33) | L3MBTL1KDM4E | |
| SCHEMBL17751433 | 0.84 | ACMSD (0.31) | L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL11922037 | 0.82 | RXRA (0.50) | RXRARXRBNPC1RAB9AL3MBTL1 | |
| SCHEMBL11922021 | 0.82 | RXRA (0.50) | RXRARXRBNPC1RAB9AL3MBTL1 | |
| SCHEMBL22130773 | 0.82 | KMO (0.33) | L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL13509047 | 0.81 | — | — | |
| SCHEMBL18564880 | 0.81 | RXRA (0.48) | RXRARXRBNPC1RAB9AL3MBTL1 | |
| SCHEMBL11922045 | 0.81 | GPR3 (0.46) | RXRARXRBNPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492260-A1 | CARBAZOLE COMPOUND AND USE THEREOF | Tosoh Corporation (JP) | 2012-08-29 | — | — | EP | disclosed |