Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LAP3 | P28838 | 2/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14579036 | 0.87 | GPR84 (0.50) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL8687358 | 0.81 | CA2 (0.43) | OPRM1CA2SPHK1CA1LMNA | |
| SCHEMBL8689590 | 0.81 | CA2 (0.54) | OPRM1CA2SPHK1CA1LMNA | |
| Hydrochloric Acid SCHEMBL8688380 | 0.79 | CA2 (0.52) | OPRM1CA2SPHK1CA1LMNA | |
| SCHEMBL28400158 | 0.79 | CA2 (0.52) | OPRM1CA2SPHK1CA1LMNA | |
| SCHEMBL4886199 | 0.78 | GPR84 (0.50) | OPRM1SPHK1LMNATP53LAP3 | |
| SCHEMBL8021744 | 0.78 | OPRM1 (0.48) | OPRM1SPHK1LMNATP53LAP3 | |
| SCHEMBL19032390 | 0.78 | CA1 (0.50) | OPRM1SPHK1CA1LMNATP53 | |
| SCHEMBL9357538 | 0.77 | CA2 (0.54) | OPRM1CA2CA1GRIK1GRIK2 | |
| SCHEMBL11144899 | 0.76 | CA1 (0.48) | OPRM1SPHK1CA1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120220753-A1 | N-Terminal Dimerization Methods with Bis-Amindino Acid and Bis-Thioimidate Derivatives | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220753-A1 | N-Terminal Dimerization Methods with Bis-Amindino Acid and Bis-Thioimidate Derivatives | ERBB2, MAX, DNPEP | OPRM1 3196/4885CA2 2964/4885SPHK1 4339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.