Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1406208 | 0.92 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL6650291 | 0.90 | L3MBTL1 (0.56) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL28576167 | 0.89 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL22587290 | 0.89 | CYP1A2 (0.50) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL28576166 | 0.89 | L3MBTL1 (0.45) | L3MBTL1KMT2APOLBGAAMGAM | |
| SCHEMBL6259054 | 0.88 | L3MBTL1 (0.47) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL7056634 | 0.86 | L3MBTL1 (0.53) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL3762538 | 0.86 | ALDH1A1 (0.41) | L3MBTL1KMT2APOLBGAAMGAM | |
| SCHEMBL11614940 | 0.85 | KMT2A (0.50) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL4800391 | 0.85 | KMT2A (0.50) | L3MBTL1KMT2APOLBCYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108410111-B | Reusable 3D printing material and preparation method thereof | 哈尔滨工程大学 | 2020-10-27 | — | — | CN | claimed |
| CN-111574782-A | Preparation process of heat-preservation type multilayer composite waterproof roll based on polyurethane | 徐磊 | 2020-08-25 | — | — | CN | claimed |
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |
| CN-113493449-B | NO donor coumarin furazan conjugate and pharmaceutical application thereof | 复旦大学 | 2024-04-30 | — | — | CN | disclosed |
| US-11945806-B2 | Stabilization of amyloidogenic immunoglobulin light chains | THE SCRIPPS RESEARCH INSTITUTE | 2024-04-02 | — | — | US | disclosed |
| CN-117776918-A | Method for preparing 4-acetobutyrate with high conversion rate and high selectivity | 江苏扬农化工股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-112778133-B | high-pH chrome tanning auxiliary agent containing multifunctional structure, and preparation method and application thereof | 南京工业大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-114516796-B | Method for preparing 5-oxo caproate | 北京化工大学 | 2023-05-26 | — | — | CN | disclosed |
| US-20220226335-A1 | Non-Peptidic Heterocycle-Containing Compounds for the Treatment of Alzheimer?s Disease | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2022-07-21 | — | — | US | disclosed |
| US-20220204485-A1 | STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | THE SCRIPPS RESEARCH INSTITUTE | 2022-06-30 | — | — | US | disclosed |
| US-4087547-A | Hexahydro-dibenzo[b,d]pyran-9-ones in treatment of glaucoma | ELI LILLY AND COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4066667-A | 9-Hydroxy-7,8,9,10-tetrahydro-6H, dibenzo[b][d] pyrans and pyranones | ABBOTT LABORATORIES (US) | 1978-01-03 | — | — | US | disclosed |
| US-4054583-A | Process for converting 2,7-dihydroxy-5-isopropylidene-9-substituted-2,6-methano-3,4,5,6-tetrahydro-2H-1-benzoxocin to trans-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo(b,d)pyran-9-one | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054581-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4024275-A | Method of reducing elevated blood pressure with dihydroxy-hexahydrodibenzo(b,d)pyrans | ELI LILLY AND COMPANY (US) | 1977-05-17 | — | — | US | disclosed |
| US-3987188-A | Hexahydro-dibenzo[b,d]pyran-9-ones as sedative drugs | ELI LILLY AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3968125-A | Dihydroxyhexahydrodibenzo[b,d]pyrans | ELI LILLY AND COMPANY (US) | 1976-07-06 | — | — | US | disclosed |
| US-3953603-A | Hexahydro-dibenzo[b,d,]pyran-9-ones as psychotropic, particularly anti-depressant drugs | ELI LILLY AND COMPANY (US) | 1976-04-27 | — | — | US | disclosed |
| US-3944673-A | Hexahydro-dibenzo[b,d]pyran-9-ones as analgesic drugs | ELI LILLY AND COMPANY (US) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220226335-A1 | Non-Peptidic Heterocycle-Containing Compounds for the Treatment of Alzheimer?s Disease | IAPP, GLP1R, APP | L3MBTL1 4462/4885KMT2A 4626/4885POLB 4582/4885 |
| US-20220204485-A1 | STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | TTR, MAP1LC3B, SAAL1 | L3MBTL1 336/4885KMT2A 4134/4885POLB 3451/4885 |
| US-11945806-B2 | Stabilization of amyloidogenic immunoglobulin light chains | TTR, MAP1LC3B, SAAL1 | L3MBTL1 336/4885KMT2A 4134/4885POLB 3451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.