Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192097 | 0.91 | SMN1; SMN2 (0.38) | FUCA1MTNR1AGLANPSR1KDM4E | |
| SCHEMBL6825744 | 0.79 | ALDH1A1 (0.35) | NPSR1ALDH1A1 | |
| SCHEMBL31677770 | 0.77 | — | — | |
| SCHEMBL16750997 | 0.77 | KDM4E (0.44) | MTNR1ANPSR1KDM4EMAPK1HIF1A | |
| SCHEMBL4663635 | 0.76 | — | — | |
| SCHEMBL14169155 | 0.76 | KMT2A (0.31) | — | |
| SCHEMBL2863034 | 0.76 | — | — | |
| SCHEMBL12017885 | 0.76 | DPP4 (0.37) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL15500189 | 0.76 | MTNR1A (0.46) | FUCA1MTNR1AKDM4EMAPK1ALDH1A1 | |
| SCHEMBL13637833 | 0.74 | GLA (0.37) | FUCA1MTNR1AGLANPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020012357-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | INTEGRAL BIOSCIENCES PVT. LTD. (IN) | 2020-01-16 | — | — | WO | disclosed |
| US-20120220567-A1 | BENZO-FUSED OXAZEPINE COMPOUNDS AS STEAROYL-COENZYME A DELTA-9 DESATURASE INHIBITORS | SCHERING CORPORATION | 2012-08-30 | — | — | US | disclosed |
| WO-2011011508-A1 | BENZO-FUSED OXAZEPINE COMPOUNDS AS STEAROYL-COENZYME A DELTA-9 DESATURASE INHIBITORS | SCHERING CORPORATION (US) | 2011-01-27 | — | — | WO | disclosed |
| US-7375108-B2 | 2-substituted pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-20 | — | — | US | disclosed |
| US-20070105873-A1 | 2-Substituted pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105873-A1 | 2-Substituted pyrimidines | TYMP, RRM2, TYMS | FUCA1 3920/4885MTNR1A 1618/4885GLA 3416/4885 |
| US-20120220567-A1 | BENZO-FUSED OXAZEPINE COMPOUNDS AS STEAROYL-COENZYME A DELTA-9 DESATURASE INHIBITORS | SCD, SCD5, CPT1A | FUCA1 3587/4885MTNR1A 690/4885GLA 1230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.