Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12019192 | 0.74 | FUCA1 (0.40) | GLAFUCA1KDM4EMAPK1HIF1A | |
| SCHEMBL14192097 | 0.71 | SMN1; SMN2 (0.38) | GLAFUCA1KDM4EMAPK1HIF1A | |
| SCHEMBL835215 | 0.69 | — | — | |
| SCHEMBL17174983 | 0.68 | FUCA1 (0.38) | GLAFUCA1KDM4EMAPK1HIF1A | |
| SCHEMBL12899990 | 0.67 | FUCA1 (0.51) | GLAFUCA1 | |
| SCHEMBL9914008 | 0.66 | FUCA1 (0.54) | GLAFUCA1 | |
| SCHEMBL14025399 | 0.66 | FUCA1 (0.54) | GLAFUCA1 | |
| SCHEMBL2863034 | 0.65 | — | — | |
| SCHEMBL4663635 | 0.65 | — | — | |
| SCHEMBL9911085 | 0.65 | LMNA (0.50) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |