Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29994706 | 1.00 | HPGD (0.62) | HPGDPOLBHTTKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL155794 | 0.98 | HPGD (0.61) | HPGDPOLBHTTKDM4EMAPT | |
| SCHEMBL2664418 | 0.84 | KDM4E (0.57) | HPGDPOLBHTTKDM4EMAPT | |
| SCHEMBL1460363 | 0.84 | KDM4E (0.70) | HPGDPOLBHTTKDM4EMAPT | |
| SCHEMBL1363239 | 0.84 | KDM4E (0.57) | HPGDPOLBHTTKDM4EMAPT | |
| SCHEMBL25397315 | 0.82 | ALDH1A1 (0.60) | KDM4EMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL6154331 | 0.82 | KDM4E (0.55) | HPGDPOLBHTTKDM4EMAPT | |
| SCHEMBL6154794 | 0.82 | MAPT (0.57) | HPGDPOLBHTTKDM4EMAPT | |
| SCHEMBL20772312 | 0.82 | KCNQ3 (0.56) | HPGDPOLBHTTKDM4EMAPT | |
| SCHEMBL29843574 | 0.82 | ALDH1A1 (0.60) | KDM4EMAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188071-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | EVOTEC INTERNATIONAL GMBH (DE) | 2025-06-12 | — | — | US | disclosed |
| US-12258338-B2 | Modulators of the integrated stress response pathway | EVOTEC INTERNATIONAL GMBH (DE) | 2025-03-25 | — | — | US | disclosed |
| EP-4144792-B1 | PARTICULATE WATER-ABSORBENT RESIN COMPOSITION, ABSORBENT BODY AND ABSORBENT ARTICLE | SUMITOMO SEIKA CHEMICALS (JP) | 2025-01-08 | — | — | EP | disclosed |
| EP-4144803-B1 | WATER ABSORBENT RESIN COMPOSITION, ABSORBENT, AND ABSORBENT ARTICLE | SUMITOMO SEIKA CHEMICALS (JP) | 2024-12-25 | — | — | EP | disclosed |
| CN-115516043-B | Particulate water-absorbent resin composition, absorber, and absorbent article | 住友精化株式会社 | 2024-06-28 | — | — | CN | disclosed |
| CN-115443312-B | Water-absorbent resin composition, absorber, and absorbent article | 住友精化株式会社 | 2024-05-14 | — | — | CN | disclosed |
| CN-110603254-B | Substituted pyrazole compounds and methods of using the same for treating hyperproliferative diseases | 班塔姆制药有限责任公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-113993850-B | Modulators of integrated stress response pathways | 埃沃特克国际有限责任公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20230182112-A1 | PARTICULATE WATER-ABSORBING RESIN COMPOSITION, PRODUCTION METHOD THEREFOR, ABSORBENT OBJECT, AND ABSORBENT ARTICLE | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2023-06-15 | — | — | US | disclosed |
| US-20230165999-A1 | ABSORBENT ARTICLE | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2023-06-01 | — | — | US | disclosed |
| US-4814349-A | Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2 alkyl and 2-cycloalkylhydrazides | AMERICAN CYANAMID COMPANY (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0171016-B1 | CYCLIC ETHERS ALPHA-SUBSTITUTED BY AN ISOCYANIDE DICHLORIDE GROUP, AND METHOD FOR THEIR PREPARATION | BAYER AG (DE) | 1988-11-09 | — | — | EP | disclosed |
| EP-0228564-A2 | Novel insecticidal diacylhydrazine compounds | AMERICAN CYANAMID COMPANY (US) | 1987-07-15 | — | — | EP | disclosed |
| US-4659844-A | CHEMICAL INTERMEDIATES FOR BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |
| EP-0171016-A2 | Cyclic ethers alpha-substituted by an isocyanide dichloride group, and method for their preparation | BAYER AG (DE) | 1986-02-12 | — | — | EP | disclosed |
| US-4309422-A | INSECTICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| US-4166129-A | AGRICULTURAL AND HORTICULTURAL N-BENZOYL-N'-TRICHLOROETHYLIDENE HYDRAZINE FUNGICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1979-08-28 | — | — | US | disclosed |
| US-4125704-A | Phenyl-substituted rubidazone analogs | SRI INTERNATIONAL (US) | 1978-11-14 | — | — | US | disclosed |
| US-4071633-A | Fungicidal N-trichloroacetyl-N'-chlorobenzoylhydrazine derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1978-01-31 | — | — | US | disclosed |
| US-4016162-A | BRONCHODILATORS | GRUPPO LEPETIT S.P.A. (IT) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12258338-B2 | Modulators of the integrated stress response pathway | CRHR2, CRHR1, CRH | HPGD 2475/4885POLB 3733/4885HTT 1664/4885 |
| US-20250188071-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | CRHR2, CRHR1, CRH | HPGD 2475/4885POLB 3733/4885HTT 1664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.