Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257892 | 0.84 | PPARG (0.38) | SOS1MAP4K4FFAR4PPARGKMT2A | |
| SCHEMBL10269849 | 0.81 | RAB9A (0.42) | KMT2ALMNAMEN1 | |
| SCHEMBL10355136 | 0.78 | ESR1 (0.61) | SOS1SLC1A3SLC1A2SLC1A1ESR1 | |
| SCHEMBL10269442 | 0.77 | KDM1A (0.40) | FFAR4PPARGSCN9ALMNA | |
| SCHEMBL10187271 | 0.77 | CES2 (0.41) | CES2CES1 | |
| SCHEMBL4336604 | 0.75 | SOS1 (0.56) | SOS1SLC1A3SLC1A2SLC1A1HTR2A | |
| SCHEMBL14656080 | 0.74 | SOS1 (0.47) | SOS1SLC1A3SLC1A2SLC1A1HTR2A | |
| SCHEMBL257856 | 0.74 | SOS1 (0.55) | SOS1SLC1A3SLC1A2SLC1A1HTR2A | |
| SCHEMBL12260900 | 0.74 | SOS1 (0.55) | SOS1SLC1A3SLC1A2SLC1A1MAP4K4 | |
| SCHEMBL5546742 | 0.74 | SOS1 (0.55) | SOS1SLC1A3SLC1A2SLC1A1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399584-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |