Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12031398 | 0.84 | SOS1 (0.50) | PPARGKMT2ALMNASOS1CHEK2 | |
| SCHEMBL10269849 | 0.80 | RAB9A (0.42) | KMT2ALMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL257919 | 0.80 | TEAD4 (0.48) | KMT2AL3MBTL1LMNAGFERMRGPRX4 | |
| SCHEMBL13191461 | 0.79 | HDAC1 (0.41) | KMT2AHDAC1HDAC6MAPTTSHR | |
| SCHEMBL28061160 | 0.78 | LTA4H (0.48) | KMT2AL3MBTL1LMNASOS1FFAR4 | |
| SCHEMBL15075246 | 0.78 | LTA4H (0.48) | L3MBTL1MRGPRX4TSHRHTTSMN1; SMN2 | |
| SCHEMBL257852 | 0.77 | SOS1 (0.50) | PPARGKMT2AL3MBTL1LMNAGFER | |
| SCHEMBL9107096 | 0.77 | MRGPRX4 (0.41) | MRGPRX4FFAR4MAPTALDH1A1 | |
| SCHEMBL12260917 | 0.77 | SOS1 (0.39) | PPARGKMT2AL3MBTL1LMNAGFER | |
| SCHEMBL10269442 | 0.76 | KDM1A (0.40) | PPARGL3MBTL1LMNAFFAR4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404607-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2012-01-11 | — | — | EP | disclosed |
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |