SCHEMBL12036366

SCHEMBL12036366

c1ccc(-c2cc(-c3ccccc3)cc(-c3cccc(-n4c5ccccc5c5cc6c7ccccc7n(-c7cccc(-c8cc(-c9ccccc9)cc(-c9ccccc9)c8)n7)c6cc54)n3)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
RAB9A P51151 1/20 0.37
KDM4E B2RXH2 5/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ATM Q13315 1/20 0.35
COMT P21964 1/20 0.34
CNR1 P21554 1/20 0.33
ASIC3 Q9UHC3 1/20 0.33
NPY5R Q15761 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MKNK1 Q9BUB5 1/20 0.31
MKNK2 Q9HBH9 1/20 0.31
DHODH Q02127 2/20 0.31
HTR6 P50406 2/20 0.31
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10061787 0.95 L3MBTL1 (0.45) KMT2AMEN1RAB9AKDM4EL3MBTL1
SCHEMBL10060928 0.94 MEN1 (0.37) KMT2AMEN1RAB9AKDM4EL3MBTL1
SCHEMBL10027589 0.93 MEN1 (0.44) KMT2AMEN1RAB9AKDM4EL3MBTL1
SCHEMBL17189508 0.92 KDM4E (0.38) KMT2AMEN1RAB9AKDM4EL3MBTL1
SCHEMBL17248218 0.92 MEN1 (0.43) KMT2AMEN1RAB9AKDM4EL3MBTL1
SCHEMBL12036316 0.90 MEN1 (0.38) KMT2AMEN1RAB9AKDM4EL3MBTL1
SCHEMBL10061797 0.90 MEN1 (0.46) KMT2AMEN1RAB9AKDM4EL3MBTL1
SCHEMBL10060778 0.90 L3MBTL1 (0.45) KMT2AMEN1RAB9AKDM4EL3MBTL1
SCHEMBL24609457 0.89 KDM4E (0.42) KMT2AMEN1RAB9AKDM4EL3MBTL1
SCHEMBL20865206 0.89 MEN1 (0.41) KMT2AMEN1RAB9AKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-06-18 US disclosed
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-06-18 US disclosed
US-8993129-B2 Fluorescence and delayed fluorescence-type organic light-emitting material and element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-8993129-B2 Fluorescence and delayed fluorescence-type organic light-emitting material and element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-8389131-B2 Material for use in phosphorescent device and organic electroluminescent device using same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2013-03-05 US disclosed
US-8389131-B2 Material for use in phosphorescent device and organic electroluminescent device using same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2013-03-05 US disclosed
EP-2511360-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2012-10-17 EP disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 US disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 US disclosed
US-20110315975-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-12-29 US disclosed
US-20110315975-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT LEF1, EML4, TEAD1 KMT2A 2796/4885MEN1 2470/4885RAB9A 4391/4885
US-20110315975-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME LEF1, ELOC, ALG3 KMT2A 1530/4885MEN1 381/4885RAB9A 1574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.