SCHEMBL24455

SCHEMBL24455

O=C(O)c1cc(Cl)c(C(=O)O)c2c(C(=O)O)cc(Cl)c(C(=O)O)c12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
TSHR P16473 3/20 0.45
TP53 P04637 1/20 0.45
CASP1 P29466 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
AKR1C2 P52895 2/20 0.43
AKR1C1 Q04828 2/20 0.43
AKR1C4 P17516 1/20 0.43
AKR1C3 P42330 1/20 0.43
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
HTT P42858 2/20 0.42
MEN1 O00255 1/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD17B10 Q99714 1/20 0.42
DPP4 P27487 1/20 0.41
POLB P06746 3/20 0.41
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29764017 1.00 ALDH1A1 (0.45) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL31401887 0.94 ALDH1A1 (0.41) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL29764032 0.93 CYP1A2 (0.44) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL30254 0.93 CYP1A2 (0.44) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL1204591 0.92 CYP1A2 (0.56) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL6738393 0.88 ALDH1A1 (0.37) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL6735101 0.82 ALDH1A1 (0.36) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL2904787 0.82 DPP4 (0.46) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL7738805 0.81 ALDH1A1 (0.45) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL2897882 0.80 AKR1C4 (0.48) ALDH1A1TSHRTP53CASP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239982-A1 THERMALLY TREATED POLYAMIC AMIDE AEROGEL Blueshift Materials, Inc. 2024-07-18 US claimed
CN-115232017-B Compound, resin and preparation method and application thereof 华为技术有限公司 2024-06-18 CN claimed
CN-118047948-A Resin, preparation method thereof and resin composition 华为技术有限公司 2024-05-17 CN claimed
US-11873379-B2 Thermally treated polyamic amide aerogel Blueshift Materials, Inc. (US) 2024-01-16 US claimed
CN-117362741-A Heat treated polyamide-amide aerogel 蓝移材料有限公司 2024-01-09 CN claimed
CN-117304037-A Diamine monomer, preparation method thereof, resin and application thereof 华为技术有限公司 2023-12-29 CN claimed
CN-111433265-B Heat treated polyamide-amide aerogel 蓝移材料有限公司 2023-09-29 CN claimed
CN-108699277-B Polymeric aerogels with improved mechanical and thermal properties 蓝移材料有限公司 2022-12-02 CN claimed
CN-115232017-A Compound, resin, and preparation method and application thereof 华为技术有限公司 2022-10-25 CN claimed
EP-3368198-B1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF BLUESHIFT MAT INC (US) 2022-07-06 EP claimed
WO-1994024191-A1 NEGATIVE BIREFRINGENT POLYIMIDE FILMS THE UNIVERSITY OF AKRON (US) 1994-10-27 WO claimed
US-5344916-A Multilayer films for optical displays using polyimide films THE UNIVERSITY OF AKRON (US) 1994-09-06 US claimed
US-5328979-A Thermoplastic copolyimides and composites therefrom THE UNIVERSITY OF AKRON (US) 1994-07-12 US claimed
EP-0362649-B1 Radiation-sensitive compositions and their use BASF AG (DE) 1994-03-02 EP claimed
US-5284734-A Insulating layers and printed circuits; precursors for polyimides and polyquinazolines BASF AKTIENGESELLSCHAFT (DE) 1994-02-08 US claimed
US-5003078-A Synthesis of phthalonitrile resins containing ether and imide linkages THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1991-03-26 US claimed
WO-1991001340-A1 POLYIMIDES COMPRISING SUBSTITUTED BENZIDINES THE UNIVERSITY OF AKRON (US) 1991-02-07 WO claimed
US-4925915-A FLUORINE CONTAINING POLYIMIDES HOECHST CELANESE CORP. (US) 1990-05-15 US claimed
EP-0362649-A2 Radiation-sensitive compositions and their use BASF Aktiengesellschaft (DE) 1990-04-11 EP claimed
EP-0317944-A2 Polymers prepared from 4,4'-bis-(2-(amino (halo) phenoxyphenyl) hexafluoroisopropyl) diphenyl ether HOECHST CELANESE CORPORATION (US) 1989-05-31 EP claimed