Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6738393 | 0.95 | ALDH1A1 (0.37) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL30254 | 0.89 | CYP1A2 (0.44) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL29764032 | 0.89 | CYP1A2 (0.44) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL29764017 | 0.82 | ALDH1A1 (0.45) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL24455 | 0.82 | ALDH1A1 (0.45) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL31401887 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL3815003 | 0.80 | CYP3A4 (0.39) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL1204591 | 0.79 | CYP1A2 (0.56) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL705877 | 0.74 | DPP4 (0.35) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL1456160 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023369-B | Process for preparing TDI based polyurethane flexible foams containing organic acid anhydrides and/or organic acid chlorides | 科思创德国股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| US-20200079895-A1 | METHOD FOR PRODUCING TDI-BASED FLEXIBLE POLYURETHANE FOAMS CONTAINING ORGANIC ACID ANHYDRIDES AND/OR ORGANIC ACID CHLORIDES | COVESTRO DEUTSCHLAND AG (DE) | 2020-03-12 | — | — | US | disclosed |
| US-20040209969-A1 | Polyisocyanate polyaddition products | ARLT ANDREAS | 2004-10-21 | — | — | US | disclosed |
| US-6800667-B1 | CATALYTIC CONDENSATION POLYMERIZATION OF POLYURETHANE FOAM USING ORGANIC AMINE OR METAL COMPOUND IN PRESENCE OF UNREACTED ACID ANHYDRIDE; MATTRESSES, UPHOLSTERY, OR CARPETS | BASF CORPORATION | 2004-10-05 | — | — | US | disclosed |
| US-6794421-B2 | comprising hydrophobic compounds plus at least one further compound and/or derivative thereof reactive toward primary amines, compound being selected from cyclic sulfonic esters and sulfones and mixtures thereof | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-21 | — | — | US | disclosed |
| US-6183869-B1 | HEAT RESISTANT RESIN, FLUORORESIN AND COUPLER WITH PRIMER FOR MULTILAYER ELEMENT | FUJI XEROX CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |