SCHEMBL30254

SCHEMBL30254

O=C(O)c1cc(Cl)c(C(=O)O)c2c(C(=O)O)c(Cl)cc(C(=O)O)c12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
ALDH1A1 P00352 4/20 0.43
TSHR P16473 3/20 0.43
TP53 P04637 1/20 0.43
CASP1 P29466 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
AKR1C2 P52895 2/20 0.42
AKR1C1 Q04828 2/20 0.42
AKR1C4 P17516 1/20 0.42
AKR1C3 P42330 1/20 0.42
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
HTT P42858 2/20 0.41
MEN1 O00255 1/20 0.41
PKM P14618 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD17B10 Q99714 1/20 0.41
POLB P06746 3/20 0.40
DPP4 P27487 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29764032 1.00 CYP1A2 (0.44) CYP1A2ALDH1A1TSHRTP53CASP1
SCHEMBL24455 0.93 ALDH1A1 (0.45) CYP1A2ALDH1A1TSHRTP53CASP1
SCHEMBL29764017 0.93 ALDH1A1 (0.45) CYP1A2ALDH1A1TSHRTP53CASP1
SCHEMBL31401887 0.91 ALDH1A1 (0.41) CYP1A2ALDH1A1TSHRTP53CASP1
SCHEMBL1204591 0.90 CYP1A2 (0.56) CYP1A2ALDH1A1TSHRTP53CASP1
SCHEMBL6735101 0.89 ALDH1A1 (0.36) CYP1A2ALDH1A1TSHRTP53CASP1
SCHEMBL6738393 0.82 ALDH1A1 (0.37) CYP1A2ALDH1A1TSHRTP53CASP1
SCHEMBL1456160 0.81 ALDH1A1 (0.50) CYP1A2ALDH1A1TSHRTP53CASP1
SCHEMBL2904787 0.81 DPP4 (0.46) CYP1A2ALDH1A1TSHRTP53CASP1
SCHEMBL7738805 0.79 ALDH1A1 (0.45) ALDH1A1TSHRTP53CASP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239982-A1 THERMALLY TREATED POLYAMIC AMIDE AEROGEL Blueshift Materials, Inc. 2024-07-18 US claimed
CN-115232017-B Compound, resin and preparation method and application thereof 华为技术有限公司 2024-06-18 CN claimed
CN-118047948-A Resin, preparation method thereof and resin composition 华为技术有限公司 2024-05-17 CN claimed
US-11873379-B2 Thermally treated polyamic amide aerogel Blueshift Materials, Inc. (US) 2024-01-16 US claimed
CN-117362741-A Heat treated polyamide-amide aerogel 蓝移材料有限公司 2024-01-09 CN claimed
CN-117304037-A Diamine monomer, preparation method thereof, resin and application thereof 华为技术有限公司 2023-12-29 CN claimed
CN-111433265-B Heat treated polyamide-amide aerogel 蓝移材料有限公司 2023-09-29 CN claimed
US-20230091989-A1 DIAMINE MONOMER COMPOUND, METHOD FOR PREPARING THE SAME, RESIN, FLEXIBLE FILM, AND ELECTRONIC DEVICE Zhen Ding Technology Co., Ltd. (TW) 2023-03-23 US claimed
US-20230086746-A1 DIAMINE MONOMER COMPOUND, METHOD FOR PREPARING THE SAME, RESIN, FLEXIBLE FILM, AND ELECTRONIC DEVICE Zhen Ding Technology Co., Ltd. (TW) 2023-03-23 US claimed
CN-108699277-B Polymeric aerogels with improved mechanical and thermal properties 蓝移材料有限公司 2022-12-02 CN claimed
WO-2002090422-A1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-11-14 WO claimed
US-20020010311-A1 From polyamic acids E.I. DU PONT DE NEMOURS AND COMPANY 2002-01-24 US claimed
US-5690961-A HYALURONIC ACID, ARTHRITIS, WOUND HEALING, COSMETICS HERCULES INCORPORATED (US) 1997-11-25 US claimed
EP-0718312-A2 Crosslinked acidic polysaccharides and their uses HERCULES INCORPORATED (US) 1996-06-26 EP claimed
EP-0362649-B1 Radiation-sensitive compositions and their use BASF AG (DE) 1994-03-02 EP claimed
US-5284734-A Insulating layers and printed circuits; precursors for polyimides and polyquinazolines BASF AKTIENGESELLSCHAFT (DE) 1994-02-08 US claimed
US-5003078-A Synthesis of phthalonitrile resins containing ether and imide linkages THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1991-03-26 US claimed
US-4925915-A FLUORINE CONTAINING POLYIMIDES HOECHST CELANESE CORP. (US) 1990-05-15 US claimed
EP-0362649-A2 Radiation-sensitive compositions and their use BASF Aktiengesellschaft (DE) 1990-04-11 EP claimed
EP-0317944-A2 Polymers prepared from 4,4'-bis-(2-(amino (halo) phenoxyphenyl) hexafluoroisopropyl) diphenyl ether HOECHST CELANESE CORPORATION (US) 1989-05-31 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230086746-A1 DIAMINE MONOMER COMPOUND, METHOD FOR PREPARING THE SAME, RESIN, FLEXIBLE FILM, AND ELECTRONIC DEVICE CDH1, RFT1, PADI1 CYP1A2 4438/4885ALDH1A1 1307/4885TSHR 3857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.