Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 6/20 | 0.54 |
| ▸ | FDPS | P14324 | 13/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12048125 | 0.92 | GGPS1 (0.59) | GGPS1FDPSPTPN5BTN3A1PDE3A | |
| SCHEMBL12048155 | 0.88 | FDPS (0.49) | GGPS1FDPSPTPN5BTN3A1PDE3A | |
| SCHEMBL12048150 | 0.87 | GGPS1 (0.46) | GGPS1FDPSPTPN5ALDH1A1 | |
| SCHEMBL12048172 | 0.86 | FDPS (0.50) | GGPS1FDPSBTN3A1PDE3ASMN1; SMN2 | |
| SCHEMBL12048146 | 0.84 | GGPS1 (0.76) | GGPS1FDPSPTPN5ALDH1A1LMNA | |
| SCHEMBL12048169 | 0.82 | GGPS1 (0.49) | GGPS1FDPS | |
| SCHEMBL11952615 | 0.81 | GGPS1 (0.52) | GGPS1FDPSALDH1A1LMNA | |
| SCHEMBL12048259 | 0.81 | GGPS1 (0.52) | GGPS1FDPS | |
| SCHEMBL12048195 | 0.80 | GGPS1 (0.51) | GGPS1FDPS | |
| SCHEMBL12048186 | 0.80 | GGPS1 (0.51) | GGPS1FDPSHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071573-B2 | Bisphosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, A BODY CORPORATE AND POLITIC OF THE STATE OF ILLINOIS (US) | 2011-12-06 | — | — | US | disclosed |
| US-7358361-B2 | Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-15 | — | — | US | disclosed |