Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 0.45 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.33 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12769566 | 1.00 | DUT (0.45) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL21418938 | 0.85 | DUT (0.48) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL23880694 | 0.84 | DUT (0.47) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL21345846 | 0.84 | DUT (0.47) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL12769572 | 0.83 | LMNA (0.36) | SLC29A1 | |
| SCHEMBL12049887 | 0.83 | LMNA (0.36) | SLC29A1 | |
| SCHEMBL10072872 | 0.83 | DUT (0.42) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL12049893 | 0.82 | DUT (0.46) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL12049891 | 0.82 | DUT (0.46) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL2106569 | 0.82 | DUT (0.46) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071567-B2 | 4′-substituted nucleoside derivatives as inhibitors of HCV RNA replication | ROCHE PALO ALTO LLC (US) | 2011-12-06 | — | — | US | disclosed |
| US-20100003213-A1 | 4'-SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION | DEVOS RENE ROBERT | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100003213-A1 | 4'-SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION | NSUN2, RNGTT, RNMT | DUT 10/4885SLC28A1 56/4885SLC28A2 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.