Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 3/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | ATIC | P31939 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.34 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.33 |
| ▸ | P2RX5 | Q93086 | 2/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.33 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.33 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12052869 | 0.97 | THRB (0.39) | THRBPHLPP2ENPP2CYP1A2CYP2C19 | |
| SCHEMBL12053192 | 0.95 | BRD4 (0.36) | THRBPHLPP2ENPP2CYP2C19HSD17B10 | |
| SCHEMBL12053138 | 0.95 | PHLPP2 (0.39) | THRBPHLPP2ENPP2CYP1A2CYP2C19 | |
| SCHEMBL12053222 | 0.94 | ATIC (0.36) | THRBPHLPP2ENPP2CYP1A2CYP2C19 | |
| SCHEMBL12053200 | 0.91 | BRD4 (0.33) | THRBPHLPP2CYP1A2CYP2C19BRD4 | |
| SCHEMBL12053204 | 0.91 | BRD4 (0.33) | THRBPHLPP2CYP1A2CYP2C19BRD4 | |
| SCHEMBL12053216 | 0.90 | ENPP2 (0.45) | THRBPHLPP2ENPP2CYP2C19BRD4 | |
| SCHEMBL12053137 | 0.90 | P2RX5 (0.34) | THRBPHLPP2ENPP2CYP2C19BRD4 | |
| SCHEMBL12053219 | 0.89 | P2RX5 (0.36) | CYP2C19ATICP2RX5P2RX4P2RX2 | |
| SCHEMBL12053165 | 0.88 | ENPP2 (0.35) | THRBPHLPP2ENPP2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8080101-B2 | Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2011-12-20 | — | — | US | disclosed |
| US-20080295732-A1 | Azo Reactive Dyes And Mixtures Of Fiber-Reactive Azo Dyes, Their Preparation And Their Use | DYSTAR TEXTILFARBEN GMBH &CO. DEUTSCHLAND KG (DE) | 2008-12-04 | — | — | US | disclosed |