Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13060801 | 0.92 | FYN (0.55) | SIGMAR1TMEM97SMN1; SMN2PARP1HPGD | |
| SCHEMBL12333454 | 0.92 | USP2 (0.55) | SIGMAR1TMEM97SMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL13060857 | 0.89 | FYN (0.52) | SIGMAR1TMEM97SMN1; SMN2PARP1HPGD | |
| SCHEMBL9490800 | 0.87 | HDAC3 (0.66) | SIGMAR1TMEM97SMN1; SMN2HDAC3SMYD3 | |
| SCHEMBL13060861 | 0.86 | BCL2 (0.56) | SIGMAR1TMEM97SMN1; SMN2HPGDKDM4E | |
| SCHEMBL12228078 | 0.84 | SMN1; SMN2 (0.57) | SIGMAR1TMEM97SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL13060639 | 0.84 | FYN (0.55) | SIGMAR1TMEM97SMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL842218 | 0.83 | NPC1 (0.59) | SIGMAR1TMEM97SMN1; SMN2HPGDKDM4E | |
| SCHEMBL18773534 | 0.83 | SMN1; SMN2 (0.60) | SIGMAR1TMEM97SMN1; SMN2HPGDKDM4E | |
| SCHEMBL14947438 | 0.82 | HPGD (0.67) | SIGMAR1TMEM97SMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084615-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2011-12-27 | — | — | US | disclosed |
| US-8084615-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100324025-A1 | Antibacterial Agents | UNIVERSITY OF WASHINGTON (US) | 2010-12-23 | — | — | US | disclosed |
| US-20100324025-A1 | Antibacterial Agents | UNIVERSITY OF WASHINGTON (US) | 2010-12-23 | — | — | US | disclosed |
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | UNIVERSITY OF WASHINGTON (US) | 2009-06-25 | — | — | US | disclosed |
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | UNIVERSITY OF WASHINGTON (US) | 2009-06-25 | — | — | US | disclosed |
| US-20070244197-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2007-10-18 | — | — | US | disclosed |
| US-20070244197-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244197-A1 | Antibacterial agents | MRPL21, SI, PGLS | SIGMAR1 776/4885TMEM97 3828/4885SMN1; SMN2 2296/4885 |
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, PGLS | SIGMAR1 776/4885TMEM97 3828/4885SMN1; SMN2 2296/4885 |
| US-20100324025-A1 | Antibacterial Agents | MRPL21, SI, PGLS | SIGMAR1 776/4885TMEM97 3828/4885SMN1; SMN2 2296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.