Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 15/20 | 0.57 |
| ▸ | FCER2 | P06734 | 2/20 | 0.57 |
| ▸ | MMP3 | P08254 | 12/20 | 0.53 |
| ▸ | MMP9 | P14780 | 8/20 | 0.53 |
| ▸ | MMP8 | P22894 | 8/20 | 0.53 |
| ▸ | MMP2 | P08253 | 8/20 | 0.53 |
| ▸ | MMP7 | P09237 | 5/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25000564 | 0.82 | MMP1 (0.63) | MMP1FCER2MMP3MMP9MMP8 | |
| SCHEMBL25139508 | 0.82 | MMP1 (0.63) | MMP1FCER2MMP3MMP9MMP8 | |
| SCHEMBL30514280 | 0.81 | MMP1 (0.61) | MMP1FCER2MMP3MMP9MMP8 | |
| SCHEMBL21988101 | 0.81 | MMP1 (0.63) | MMP1FCER2MMP3MMP9MMP8 | |
| SCHEMBL12412728 | 0.80 | MMP1 (0.51) | MMP1MMP3MMP9MMP8MMP2 | |
| SCHEMBL7066963 | 0.80 | MMP1 (0.61) | MMP1FCER2MMP3MMP9MMP8 | |
| SCHEMBL989841 | 0.80 | PSMB5 (0.64) | MMP1FCER2MMP3MMP8MMP2 | |
| SCHEMBL7066966 | 0.80 | MMP1 (0.61) | MMP1FCER2MMP3MMP9MMP8 | |
| SCHEMBL13956887 | 0.80 | PSMB5 (0.67) | MMP1FCER2MMP3MMP9MMP8 | |
| SCHEMBL15759462 | 0.80 | PSMB5 (0.64) | MMP1FCER2MMP3MMP8MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8080250-B1 | Immunoconjugates with an intracellularly-cleavable linkage | IMMUNOMEDICS, INC. (US) | 2011-12-20 | — | — | US | disclosed |