Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 16/20 | 0.51 |
| ▸ | MMP3 | P08254 | 16/20 | 0.51 |
| ▸ | MMP8 | P22894 | 5/20 | 0.49 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 9/20 | 0.48 |
| ▸ | MMP7 | P09237 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14821599 | 0.83 | MMP1 (0.57) | MMP1MMP3MMP8MMP9MMP2 | |
| SCHEMBL20159738 | 0.83 | MMP2 (0.57) | MMP1MMP3MMP8MMP9MMP2 | |
| SCHEMBL13344145 | 0.82 | GHSR (0.57) | MMP1MMP3MMP8MMP2 | |
| SCHEMBL20356789 | 0.82 | GHSR (0.57) | MMP1MMP3MMP8MMP2 | |
| SCHEMBL12062789 | 0.80 | MMP1 (0.57) | MMP1MMP3MMP8MMP9MMP2 | |
| SCHEMBL16854865 | 0.80 | CALCRL (0.54) | CALCRL | |
| SCHEMBL23901052 | 0.80 | MMP2 (0.54) | MMP1MMP3MMP8MMP9MMP2 | |
| SCHEMBL23893967 | 0.79 | MMP2 (0.53) | MMP1MMP3MMP8MMP9MMP2 | |
| SCHEMBL16984908 | 0.77 | CALCRL (0.51) | CALCRL | |
| SCHEMBL25062089 | 0.77 | MMP2 (0.53) | MMP1MMP3MMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE48751-E1 | Immunoconjugates with an intracellularly-cleavable linkage | IMMUNOMEDICS, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-8759496-B2 | Immunoconjugates with an intracellularly-cleavable linkage | IMMUNOMEDICS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-7999083-B2 | Immunoconjugates with an intracellularly-cleavable linkage | IMMUNOMEDICS, INC. (US) | 2011-08-16 | — | — | US | disclosed |