Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.61 |
| ▸ | MMP8 | P22894 | 4/20 | 0.61 |
| ▸ | FCER2 | P06734 | 2/20 | 0.60 |
| ▸ | MMP2 | P08253 | 12/20 | 0.55 |
| ▸ | MMP3 | P08254 | 6/20 | 0.55 |
| ▸ | MMP9 | P14780 | 3/20 | 0.55 |
| ▸ | MMP7 | P09237 | 2/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066966 | 1.00 | MMP1 (0.61) | MMP1MMP8FCER2MMP2MMP3 | |
| SCHEMBL7391831 | 0.89 | MMP1 (0.57) | MMP1MMP8FCER2MMP2MMP3 | |
| SCHEMBL15759462 | 0.88 | PSMB5 (0.64) | MMP1MMP8FCER2MMP2MMP3 | |
| SCHEMBL989841 | 0.88 | PSMB5 (0.64) | MMP1MMP8FCER2MMP2MMP3 | |
| SCHEMBL20457125 | 0.88 | MMP8 (0.71) | MMP1MMP8MMP9MMEACE | |
| SCHEMBL23376907 | 0.87 | MMP1 (0.56) | MMP1MMP8FCER2MMP2MMP3 | |
| SCHEMBL13956893 | 0.87 | MMP1 (0.60) | MMP1MMP8FCER2MMP2MMP3 | |
| SCHEMBL14761375 | 0.87 | CHRNB2 (0.58) | MMEACE | |
| SCHEMBL7128547 | 0.86 | MME (0.51) | MMEACE | |
| SCHEMBL7128546 | 0.86 | MME (0.51) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | disclosed |