SCHEMBL120657

SCHEMBL120657

CC(C)OC(=O)C1CC2=CC(=O)CCC2(C)C2(C)CCC3C(CCC34CCC(=O)O4)C12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 8/20 0.49
AR P10275 7/20 0.49
NR3C1 P04150 6/20 0.49
NR3C2 P08235 4/20 0.49
LMNA P02545 5/20 0.38
HTR2B P41595 3/20 0.38
ABCB11 O95342 2/20 0.38
CHRM2 P08172 2/20 0.38
CYP2C19 P33261 2/20 0.38
ADRA1A P35348 2/20 0.38
MAPT P10636 2/20 0.38
BLM P54132 2/20 0.38
CYP3A4 P08684 1/20 0.38
NFKB1 P19838 1/20 0.38
HIF1A Q16665 1/20 0.38
ESR1 P03372 1/20 0.38
ABCB1 P08183 1/20 0.38
OPRK1 P41145 1/20 0.38
ESR2 Q92731 1/20 0.38
SLC47A1 Q96FL8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20554 0.92 PGR (0.58) PGRARNR3C1NR3C2LMNA
SCHEMBL14598809 0.77 PGR (0.66) PGRARNR3C1NR3C2LMNA
SCHEMBL5395577 0.76 SHBG (0.46) PGRARNR3C1LMNAHTR2B
Dicirenone SCHEMBL120656 0.72 NR3C1 (0.66) PGRARNR3C1NR3C2LMNA
SCHEMBL14592050 0.68 NR3C1 (0.74) PGRARNR3C1NR3C2LMNA
SCHEMBL14284887 0.68 NR3C1 (0.71) PGRARNR3C1NR3C2LMNA
SCHEMBL14450063 0.68 NR3C1 (0.71) PGRARNR3C1NR3C2LMNA
SCHEMBL19505433 0.67 NR3C1 (0.74) PGRARNR3C1NR3C2LMNA
SCHEMBL18387204 0.67 NR3C1 (0.74) PGRARNR3C1NR3C2LMNA
SCHEMBL14284956 0.67 NR3C1 (0.74) PGRARNR3C1NR3C2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8715735-B2 Stabilised supersaturated solids of lipophilic drugs BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-05-06 US claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
EP-2087883-B1 Stabilised supersaturated solid solutions of steroidal drugs Bayer Pharma AG (DE) 2012-07-25 EP claimed
CN-1984644-B Stable supersaturated solids of lipophilic drugs BAYER SCHERING AG 2010-12-08 CN claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1765290-B1 STABILISED SUPERSATURATED SOLID SOLUTIONS OF STEROIDAL DRUGS BAYER SCHERING PHARMA AG (DE) 2009-09-09 EP claimed
EP-2087883-A1 Stabilised supersaturated solid solutions of steroidal drugs Bayer Schering Pharma Aktiengesellschaft (DE) 2009-08-12 EP claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
CN-1984644-A Stable supersaturated solids of lipophilic drugs SCHERING AG (DE) 2007-06-20 CN claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-1765290-A2 STABILISED SUPERSATURATED SOLID SOLUTIONS OF STEROIDAL DRUGS Schering Aktiengesellschaft (DE) 2007-03-28 EP claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
WO-2005087199-A2 STABILISED SUPERSATURATED SOLID SOLUTIONS OF STEROIDAL DRUGS SCHERING AKTIENGESELLSCHAFT (DE) 2005-09-22 WO claimed
US-20050207990-A1 Stabilised supersaturated solids of lipophilic drugs BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2005-09-22 US claimed