Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | POLRMT | O00411 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12066945 | 1.00 | CYP3A4 (0.33) | CYP3A4CYP2C9POLRMT | |
| SCHEMBL12067496 | 0.94 | CYP3A4 (0.33) | CYP3A4CYP2C9POLRMT | |
| SCHEMBL12068858 | 0.93 | POLRMT (0.32) | POLRMT | |
| SCHEMBL12066944 | 0.89 | CYP3A4 (0.47) | CYP3A4CYP2C9POLRMT | |
| SCHEMBL12066943 | 0.89 | CYP3A4 (0.47) | CYP3A4CYP2C9POLRMT | |
| SCHEMBL12067528 | 0.83 | CYP3A4 (0.40) | CYP3A4CYP2C9 | |
| SCHEMBL14845673 | 0.82 | TMPRSS2 (0.31) | — | |
| SCHEMBL10142784 | 0.82 | TMPRSS2 (0.31) | — | |
| SCHEMBL14845667 | 0.82 | TMPRSS2 (0.31) | — | |
| SCHEMBL12066935 | 0.80 | POLRMT (0.34) | POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011150288-A1 | 1'-SUBSTITUTED-CARBA-NUCLEOSIDE PRODRUGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2011-12-01 | — | — | WO | disclosed |