Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NMT1 | P30419 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SGK1 | O00141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508903 | 0.91 | HTR6 (0.46) | HTR6MCL1POLBACLYNMT1 | |
| SCHEMBL9202314 | 0.83 | CYP2C9 (0.49) | HTR6MCL1ACLYGAASMN1; SMN2 | |
| SCHEMBL6097407 | 0.81 | MCL1 (0.45) | HTR6MCL1ACLYNMT1SGK1 | |
| SCHEMBL13677614 | 0.75 | HTR6 (0.44) | HTR6MCL1ACLYGAANMT1 | |
| SCHEMBL16508907 | 0.74 | TSHR (0.48) | GAANMT1SMN1; SMN2MAPTCA1 | |
| SCHEMBL3956139 | 0.73 | ACLY (0.51) | HTR6MCL1ACLYGAANMT1 | |
| SCHEMBL14154814 | 0.70 | FPR2 (0.40) | HTR6MCL1ACLYGAANMT1 | |
| SCHEMBL3941116 | 0.70 | L3MBTL1 (0.42) | HTR6MCL1ACLYGAANMT1 | |
| SCHEMBL6205744 | 0.70 | L3MBTL1 (0.42) | HTR6MCL1ACLYGAANMT1 | |
| SCHEMBL2650212 | 0.70 | L3MBTL1 (0.46) | HTR6MCL1POLBACLYGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149841-A1 | SUBSTITUTED THIAZOLIDINEDIONE INDAZOLES, INDOLES AND BENZOTRIAZOLES AS ESTROGEN-RELATED RECEPTOR-α MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-12-01 | — | — | WO | disclosed |