Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12067419 | 0.81 | KMT2A (0.35) | CYP2C19KMT2AOPRD1PTGS1PTGS2 | |
| SCHEMBL490284 | 0.73 | KMT2A (0.51) | KMT2APTGS1PTGS2KCNA5MEN1 | |
| SCHEMBL27433662 | 0.73 | CYP2C19 (0.47) | CYP2C19KMT2APTGS1PTGS2MEN1 | |
| SCHEMBL9114061 | 0.72 | CYP2C19 (0.67) | CYP2C19KMT2AOPRD1PTGS1PTGS2 | |
| SCHEMBL10975454 | 0.72 | CYP2C19 (0.49) | CYP2C19KMT2AOPRD1MEN1MMP8 | |
| SCHEMBL19275401 | 0.71 | CA12 (0.50) | KMT2AMMP8ALDH1A1SMN1; SMN2 | |
| SCHEMBL24313823 | 0.69 | CYP1A2 (0.50) | CYP2C19KMT2AMMP8ALDH1A1SMN1; SMN2 | |
| SCHEMBL22474313 | 0.69 | KMT2A (0.44) | KMT2AMMP8ALDH1A1SMN1; SMN2 | |
| SCHEMBL10061860 | 0.69 | KCNA5 (0.50) | KMT2APTGS1PTGS2KCNA5MEN1 | |
| SCHEMBL4352840 | 0.69 | LMNA (0.52) | KMT2AMMP8ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151436-A2 | NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |