Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | STAMBP | O95630 | 1/20 | 0.36 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12068101 | 0.84 | RAB9A (0.40) | PTGESRAB9AHPGDKDM4EMEN1 | |
| SCHEMBL12068100 | 0.83 | KDM4E (0.44) | PTGESRAB9AHPGDKDM4EMEN1 | |
| SCHEMBL10215341 | 0.81 | MAPT (0.46) | PTGESRAB9AHPGDKDM4EMEN1 | |
| SCHEMBL10216323 | 0.80 | LMNA (0.48) | PTGESRAB9AHPGDKDM4EMEN1 | |
| SCHEMBL10216326 | 0.77 | LMNA (0.40) | PTGESRAB9AHPGDKDM4EMEN1 | |
| SCHEMBL10216327 | 0.76 | ROCK2 (0.42) | PTGESRAB9AHPGDKDM4EMEN1 | |
| SCHEMBL10215639 | 0.70 | LMNA (0.47) | PTGESRAB9AHPGDKDM4EMEN1 | |
| SCHEMBL10215346 | 0.70 | RAB9A (0.48) | PTGESRAB9AHPGDKDM4EMEN1 | |
| SCHEMBL10216328 | 0.69 | LMNA (0.46) | PTGESRAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL10216329 | 0.68 | LMNA (0.43) | PTGESRAB9AHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011156610-A2 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD SCIENCES, INC. (US) | 2011-12-15 | — | — | WO | disclosed |