Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | STAMBP | O95630 | 1/20 | 0.36 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12068100 | 0.89 | KDM4E (0.44) | RAB9AALDH1A1POLBNPC1SMN1; SMN2 | |
| SCHEMBL12068693 | 0.84 | PTGES (0.38) | RAB9AALDH1A1POLBNPC1SMN1; SMN2 | |
| SCHEMBL10215328 | 0.82 | ALDH1A1 (0.44) | RAB9AALDH1A1POLBNPC1SMN1; SMN2 | |
| SCHEMBL12066784 | 0.80 | SCD (0.37) | HPGDTSHRHSD17B13 | |
| SCHEMBL10215374 | 0.80 | RAB9A (0.51) | RAB9AALDH1A1POLBNPC1SMN1; SMN2 | |
| SCHEMBL10215288 | 0.77 | RAB9A (0.42) | RAB9AALDH1A1POLBNPC1SMN1; SMN2 | |
| SCHEMBL10215609 | 0.72 | ADORA2A (0.46) | RAB9AALDH1A1POLBNPC1MEN1 | |
| SCHEMBL10216317 | 0.70 | RAB9A (0.52) | RAB9AALDH1A1POLBNPC1SMN1; SMN2 | |
| SCHEMBL10215373 | 0.70 | RAB9A (0.51) | RAB9AALDH1A1POLBNPC1SMN1; SMN2 | |
| SCHEMBL10215554 | 0.68 | RAB9A (0.49) | RAB9AALDH1A1POLBNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011156610-A2 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD SCIENCES, INC. (US) | 2011-12-15 | — | — | WO | disclosed |