Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561626 | 0.81 | GPR35 (0.47) | GPR35ESR1ESR2PDE4DKDM4E | |
| SCHEMBL13637175 | 0.80 | GPR35 (0.40) | GPR35ESR1ESR2PDE4DHIF1A | |
| SCHEMBL14392924 | 0.77 | GPR35 (0.44) | GPR35ESR1ESR2PDE4DKDM4E | |
| SCHEMBL8203371 | 0.75 | GPR35 (0.32) | GPR35 | |
| SCHEMBL2624139 | 0.74 | GPR35 (0.36) | GPR35ESR1ESR2HIF1AEPAS1 | |
| SCHEMBL3627208 | 0.72 | TDO2 (0.51) | KDM4EL3MBTL1ALDH1A1HPGDTSHR | |
| SCHEMBL1952047 | 0.72 | USP2 (0.39) | GPR35ESR1PDE4DTUBB1KDM4E | |
| SCHEMBL6875131 | 0.72 | MAPT (0.40) | GPR35ESR1ESR2PDE4DHIF1A | |
| SCHEMBL10082469 | 0.72 | PDE4D (0.40) | GPR35PDE4DHIF1AEPAS1KDM4E | |
| SCHEMBL14393065 | 0.71 | PDE4D (0.35) | GPR35PDE4DHIF1AEPAS1TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011150190-A2 | HCV INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | ANACOR PHARMACEUTICALS, INC. (US) | 2011-12-01 | — | — | WO | disclosed |