Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070943 | 0.75 | GPR35 (0.40) | GPR35 | |
| SCHEMBL561626 | 0.70 | GPR35 (0.47) | GPR35 | |
| SCHEMBL2624139 | 0.69 | GPR35 (0.36) | GPR35 | |
| SCHEMBL13637175 | 0.69 | GPR35 (0.40) | GPR35 | |
| SCHEMBL6875131 | 0.67 | MAPT (0.40) | GPR35 | |
| SCHEMBL14392924 | 0.67 | GPR35 (0.44) | GPR35 | |
| SCHEMBL10082469 | 0.62 | PDE4D (0.40) | GPR35 | |
| SCHEMBL1952047 | 0.62 | USP2 (0.39) | GPR35 | |
| SCHEMBL3627208 | 0.62 | TDO2 (0.51) | — | |
| SCHEMBL997481 | 0.62 | ADORA2A (0.33) | GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011113859-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV | ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC (US) | 2011-09-22 | — | — | WO | disclosed |
| WO-2008096002-A1 | HCV INHIBITING MACROCYCLIC PHOSPHONATES AND AMIDOPHOSPHATES | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-08-14 | — | — | WO | disclosed |