Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | KDM5A | P29375 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31723052 | 0.83 | PDE2A (0.47) | RAB9ASMN1; SMN2NPC1POLBMAOB | |
| SCHEMBL12076388 | 0.82 | RAB9A (0.68) | RAB9ASMN1; SMN2NPC1POLBKDM4E | |
| SCHEMBL23692893 | 0.81 | RAB9A (0.67) | RAB9ASMN1; SMN2NPC1POLBKDM4E | |
| SCHEMBL30251641 | 0.80 | KDM4E (0.57) | RAB9ASMN1; SMN2NPC1POLBKDM4E | |
| SCHEMBL7266145 | 0.80 | KDM4E (0.57) | RAB9ASMN1; SMN2NPC1POLBKDM4E | |
| SCHEMBL1254744 | 0.79 | RAB9A (0.68) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL30350652 | 0.79 | RAB9A (0.68) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL20377582 | 0.79 | MAOB (0.75) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL1643163 | 0.79 | MAPT (0.58) | RAB9ASMN1; SMN2NPC1POLBKDM4E | |
| SCHEMBL18109863 | 0.78 | KDM4E (0.45) | RAB9ASMN1; SMN2NPC1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12103921-B2 | Chemical compounds | PFIZER INC. (US) | 2024-10-01 | — | — | US | disclosed |
| US-20230382892-A1 | Chemical Compounds | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-11702405-B2 | Chemical compounds | PFIZER INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20220348555-A1 | Chemical Compounds | PFIZER INC. (US) | 2022-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702405-B2 | Chemical compounds | HBZ, HBB, HBS1L | RAB9A 1684/4885SMN1; SMN2 447/4885NPC1 2812/4885 |
| US-20230382892-A1 | Chemical Compounds | HBZ, HBB, HBS1L | RAB9A 1684/4885SMN1; SMN2 447/4885NPC1 2812/4885 |
| US-12103921-B2 | Chemical compounds | HBZ, HBB, HBS1L | RAB9A 1684/4885SMN1; SMN2 447/4885NPC1 2812/4885 |
| US-20220348555-A1 | Chemical Compounds | HBZ, HBB, HBS1L | RAB9A 1684/4885SMN1; SMN2 447/4885NPC1 2812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.