Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11956926 | 0.90 | FAAH (0.46) | FAAHGPR119GLS | |
| SCHEMBL1103879 | 0.86 | GPR119 (0.47) | FAAHGPR119GLS | |
| SCHEMBL11956922 | 0.84 | GPR119 (0.45) | FAAHGPR119GLS | |
| SCHEMBL1103877 | 0.83 | FAAH (0.41) | FAAHGPR119GLS | |
| SCHEMBL1103872 | 0.77 | GPR119 (0.40) | FAAHGPR119GLS | |
| SCHEMBL8820929 | 0.75 | GPR119 (0.55) | FAAHGPR119 | |
| SCHEMBL1532854 | 0.74 | ITGB3 (0.55) | FAAHGPR119 | |
| SCHEMBL1092551 | 0.74 | FAAH (0.44) | FAAHGPR119 | |
| SCHEMBL386442 | 0.74 | EPHA2 (0.46) | GPR119 | |
| SCHEMBL27035708 | 0.74 | GPR119 (0.49) | FAAHGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258156-B2 | Compounds and compositions as modulators of GPR119 activity | IRM LLC (BM) | 2012-09-04 | — | — | US | disclosed |