SCHEMBL1208752

SCHEMBL1208752

OB(O)Oc1c2ccccc2c(-c2ccc3ccccc3c2)c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
ALOX5 P09917 3/20 0.40
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
GPR84 Q9NQS5 1/20 0.38
GSTP1 P09211 1/20 0.37
ERN1 O75460 1/20 0.37
PDE9A O76083 1/20 0.36
IKBKB O14920 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
ACMSD Q8TDX5 1/20 0.34
CYP1A2 P05177 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30413770 1.00 ESR1 (0.41) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL30761752 0.89 ALDH1A1 (0.41) ALOX5CYP1A2CYP2D6CYP2C9TSHR
SCHEMBL29350362 0.80 ESR1 (0.52) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL36279 0.80 ESR1 (0.52) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL2379728 0.80 ESR1 (0.52) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL5556127 0.80 MGLL (0.41) ESR1ESR2CA1CA2
SCHEMBL2447870 0.79 ACHE (0.38) ESR1ESR2CA1CA2GPR84
SCHEMBL25060858 0.78 ESR1 (0.50) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL25566510 0.78 ESR1 (0.50) ESR1ESR2ALOX5HSD17B1HSD17B2
Methane SCHEMBL27979911 0.78 ESR1 (0.50) ESR1ESR2ALOX5HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2261302-B2 ORGANIC ELECTROLUMINESCENCE DEVICE AND ANTHRACENE DERIVATIVE IDEMITSU KOSAN CO (JP) 2019-05-08 EP disclosed
US-20170125687-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ANTHRACENE DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2017-05-04 US disclosed
US-9583716-B2 Organic electroluminescence device and anthracene derivative IDEMITSU KOSAN CO., LTD. (JP) 2017-02-28 US disclosed
EP-2261302-B1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ANTHRACENE DERIVATIVE IDEMITSU KOSAN CO (JP) 2016-04-20 EP disclosed
EP-2145937-B2 Organic electroluminescence device and anthracene derivative IDEMITSU KOSAN CO (JP) 2016-03-02 EP disclosed
US-20140291653-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ANTHRACENE DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2014-10-02 US disclosed
US-8785006-B2 Organic electroluminescence device and anthracene derivative IDEMITSU KOSAN CO., LTD. (JP) 2014-07-22 US disclosed
US-8318324-B2 Organic electroluminescence device and anthracene derivative IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-20120235561-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ANTHRACENE DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2012-09-20 US disclosed
EP-2145937-B1 Organic electroluminescence device and anthracene derivative IDEMITSU KOSAN CO (JP) 2012-04-25 EP disclosed
US-20110034744-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ANTHRACENE DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2011-02-10 US disclosed
EP-2261302-A1 Organic electroluminescence device and anthracene derivative Idemitsu Kosan Co., Ltd. (JP) 2010-12-15 EP disclosed
US-7839074-B2 A light emitting thin film between the cathode and the anode,which comprises an anthracene derivative, for example, 9-(4-(fluoroanthen-3-yl)phenyl)-),10-(fluoranthen-3-yl)-anthracene; also an aryamine compound such as TBDB; great efficiency of light emission, having a long life IDEMITSU KOSAN CO., LTD. (JP) 2010-11-23 US disclosed
EP-2145937-A1 Organic electroluminescence device and anthracene derivative Idemitsu Kosan Co., Ltd. (JP) 2010-01-20 EP disclosed
EP-1553154-B1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ANTHRACENE DERIVATIVE IDEMITSU KOSAN CO (JP) 2009-12-23 EP disclosed
US-20060043858-A1 Organic electroluminescence device and anthracene derivative IDEMITSU KOSAN CO., LTD. (JP) 2006-03-02 US disclosed
EP-1553154-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ANTHRACENE DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2005-07-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034744-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ANTHRACENE DERIVATIVE ALKBH2, DNA2, ANXA7 ESR1 14/4885ESR2 94/4885ALOX5 808/4885
US-20170125687-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ANTHRACENE DERIVATIVE ALKBH2, L1CAM, ALKBH3 ESR1 42/4885ESR2 80/4885ALOX5 1764/4885
US-20120235561-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ANTHRACENE DERIVATIVE ALKBH2, DNA2, ANXA7 ESR1 14/4885ESR2 94/4885ALOX5 808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.