SCHEMBL12088697

SCHEMBL12088697

c1ccc2c(c1)cc(-n1c3ccccc3c3ccc(-c4ccc5c(c4)c4ccccc4n5-c4cccc5c4sc4ccccc45)cc31)c1ccccc12

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.37
PRKDC P78527 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25671829 0.91 ALOX5 (0.43) ALOX5PRKDCTNKSTNKS2
SCHEMBL12088895 0.90 ALOX5 (0.39) ALOX5PRKDCTDP1CYP1A2TNKS
SCHEMBL17562308 0.89 ALOX5 (0.43) ALOX5PRKDCTNKSTNKS2
SCHEMBL16373669 0.89 ALOX5 (0.43) ALOX5PRKDCTNKSTNKS2
SCHEMBL12088698 0.89 ALOX5 (0.35) ALOX5PRKDCTDP1
SCHEMBL780864 0.88 ALOX5 (0.50) ALOX5PRKDCTDP1CYP1A2CYP2C9
SCHEMBL780768 0.88 ALOX5 (0.50) ALOX5PRKDCCYP1A2CYP2C9CYP2C19
SCHEMBL11885216 0.87 ALOX5 (0.46) ALOX5PRKDCTNKSTNKS2
SCHEMBL23468825 0.86 ALOX5 (0.41) ALOX5PRKDCTDP1CYP1A2TNKS
SCHEMBL16641532 0.86 ALOX5 (0.41) ALOX5PRKDCTNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-10230057-B2 Biscarbazole derivatives and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2019-03-12 US disclosed
US-20180047917-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD (JP) 2018-02-15 US disclosed
US-20180047917-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD (JP) 2018-02-15 US disclosed
US-9818958-B2 Biscarbazole derivatives and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2017-11-14 US disclosed
US-9818958-B2 Biscarbazole derivatives and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2017-11-14 US disclosed
US-20160240795-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-08-18 US disclosed
US-20160240795-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-08-18 US disclosed
US-9373802-B2 Biscarbazole derivatives and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2016-06-21 US disclosed
US-9373802-B2 Biscarbazole derivatives and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2016-06-21 US disclosed
US-20140312331-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2014-10-23 US disclosed
US-20140312331-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2014-10-23 US disclosed
US-8803134-B2 Biscarbazole derivatives and organic electroluminescence IDEMITSU KOSAN CO., LTD. (JP) 2014-08-12 US disclosed
US-8803134-B2 Biscarbazole derivatives and organic electroluminescence IDEMITSU KOSAN CO., LTD. (JP) 2014-08-12 US disclosed
US-20120223295-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2012-09-06 US disclosed
US-20120223295-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2012-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 ALOX5 3499/4885PRKDC 3445/4885TDP1 2409/4885
US-20180047917-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME EED, GABRE, EML4 ALOX5 747/4885PRKDC 3040/4885TDP1 2592/4885
US-20120223295-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE EED, GABRE, EML4 ALOX5 877/4885PRKDC 3069/4885TDP1 2754/4885
US-10230057-B2 Biscarbazole derivatives and organic electroluminescence device employing the same EED, GABRE, EML4 ALOX5 747/4885PRKDC 3040/4885TDP1 2592/4885
US-20140312331-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE EED, GABRE, EML4 ALOX5 877/4885PRKDC 3069/4885TDP1 2754/4885
US-20160240795-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME EED, GABRE, EML4 ALOX5 747/4885PRKDC 3040/4885TDP1 2592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.