Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1820670 | 1.00 | RAB9A (0.47) | RAB9ACA12MMP2MMP9MMP8 | |
| SCHEMBL26130707 | 0.84 | RAB9A (0.49) | RAB9ACA12MMP2MMP9MMP8 | |
| SCHEMBL20288937 | 0.84 | RAB9A (0.49) | RAB9ACA12MMP2MMP9MMP8 | |
| SCHEMBL14223257 | 0.83 | FPR2 (0.47) | CA12MMP2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4124134 | 0.82 | TSHR (0.47) | RAB9ACA12SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL4124137 | 0.82 | TSHR (0.47) | RAB9ACA12SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL7083712 | 0.80 | ALDH1A1 (0.58) | RAB9AMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8996223 | 0.79 | KIF11 (0.47) | CA12MMP2MEN1KMT2AALDH1A1 | |
| SCHEMBL20270154 | 0.79 | RAB9A (0.44) | RAB9ACA12MMP2MMP9MMP8 | |
| SCHEMBL20269812 | 0.79 | RAB9A (0.44) | RAB9ACA12MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196512-A1 | PROPARGYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT MODULATE BRD4 | Plexium, Inc. (US) | 2023-10-12 | — | — | WO | disclosed |
| EP-2496558-A1 | THETRAHYDROQUINOLINES DERIVATIVES AS BROMODOMAIN INHIBITORS | GlaxoSmithKline LLC (US) | 2012-09-12 | — | — | EP | disclosed |