SCHEMBL12099239

SCHEMBL12099239

N#Cc1cc(Cl)cnc1C#N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
KDM4E B2RXH2 4/20 0.41
POLB P06746 1/20 0.41
CSNK1A1 P48729 1/20 0.38
CLK4 Q9HAZ1 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP11B2 P19099 2/20 0.38
CYP11B1 P15538 1/20 0.38
CYP1A2 P05177 3/20 0.33
CYP2C9 P11712 3/20 0.33
CYP2C19 P33261 3/20 0.33
CYP3A4 P08684 2/20 0.33
HPGD P15428 2/20 0.33
PIK3CD O00329 1/20 0.33
GAA P10253 1/20 0.33
CYP2D6 P10635 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30681117 0.80 ALDH1A1 (0.56) ALDH1A1KDM4ECSNK1A1CLK4TDP1
SCHEMBL1031743 0.80 ALDH1A1 (0.56) ALDH1A1KDM4ECSNK1A1CLK4TDP1
SCHEMBL186605 0.80 KDM4E (0.47) ALDH1A1KDM4EPOLBCYP11B2CYP2C9
SCHEMBL15900365 0.80 KDM4E (0.34) ALDH1A1KDM4EPOLB
SCHEMBL11155546 0.77 KDM4E (0.40) ALDH1A1KDM4EPOLBTDP1NPSR1
SCHEMBL20782231 0.77 CYP11B2 (0.38) ALDH1A1KDM4ECSNK1A1CLK4TDP1
SCHEMBL12838156 0.77 KDM4E (0.40) ALDH1A1KDM4EPOLBTDP1NPSR1
SCHEMBL10177952 0.77 CHRNB2 (0.40) ALDH1A1KDM4ECSNK1A1CLK4TDP1
SCHEMBL4586295 0.77 KDM4E (0.40) ALDH1A1KDM4EPOLBHPGDPIK3CD
SCHEMBL1973193 0.77 ALDH1A1 (0.40) ALDH1A1KDM4EPOLBTDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9005856-B2 Hydroxygallium porphyrazine derivative mixture and electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2015-04-14 US disclosed
US-20120231380-A1 HYDROXYGALLIUM PORPHYRAZINE DERIVATIVE MIXTURE AND ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2012-09-13 US disclosed