Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | USP8 | P40818 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186605 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL4918585 | 0.78 | NOS3 (0.46) | KDM4EALDH1A1POLBPIK3CDGRM5 | |
| SCHEMBL12099239 | 0.77 | ALDH1A1 (0.41) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL12941448 | 0.77 | HTT (0.42) | KDM4EALDH1A1L3MBTL1PIK3CDHTT | |
| SCHEMBL19251508 | 0.77 | KDM4E (0.33) | KDM4EALDH1A1POLBPIK3CD | |
| SCHEMBL1973193 | 0.75 | ALDH1A1 (0.40) | KDM4EALDH1A1POLBMAPTMAPK1 | |
| SCHEMBL2298550 | 0.75 | EGLN2 (0.40) | KDM4EALDH1A1POLBS1PR3S1PR1 | |
| SCHEMBL11155546 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1POLBMAPTMAPK1 | |
| SCHEMBL12838156 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1POLBMAPTMAPK1 | |
| SCHEMBL2076123 | 0.75 | CHEK1 (0.37) | KDM4EALDH1A1POLBKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070088028-A1 | 17-Acetamido-4-azasteroid derivatives as androgen receptor modulators | MERCK & CO., INC. | 2007-04-19 | — | — | US | claimed |
| US-20060287349-A1 | 17-HETEROCYCLIC-4-AZASTEROID DERIVATIVES AS ANDROGEN RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. | 2006-12-21 | — | — | US | claimed |
| CN-119528804-A | 2- { [2- (Phenoxymethyl) pyridin-5-yl ] oxy } ethanamine derivatives and related compounds as pest control agents, for example, for protecting plants | 发现号收购集团 | 2025-02-28 | — | — | CN | disclosed |
| CN-119285538-A | 2- { [2- (Phenoxymethyl) pyridin-5-yl ] oxy } ethanamine derivatives and related compounds as pest control agents, for example, for protecting plants | 发现号收购集团 | 2025-01-10 | — | — | CN | disclosed |
| US-20240109860-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2024-04-04 | — | — | US | disclosed |
| US-20240059691-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2024-02-22 | — | — | US | disclosed |
| US-11827616-B2 | Heterocyclic compounds as pesticides | DISCOVERY PURCHASER CORPORATION (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827616-B2 | Heterocyclic compounds as pesticides | DISCOVERY PURCHASER CORPORATION (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827616-B2 | Heterocyclic compounds as pesticides | DISCOVERY PURCHASER CORPORATION (US) | 2023-11-28 | — | — | US | disclosed |
| EP-4255900-A2 | ENZYME INHIBITORS | Kalvista Pharmaceuticals Limited (GB) | 2023-10-11 | — | — | EP | disclosed |
| US-20230286918-A1 | MANUFACTURING PROCESS FOR 3,5-DICHLOROPICOLINONITRILE FOR SYNTHESIS OF VADADUSTAT | AKEBIA THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | US | disclosed |
| US-20080125399-A1 | 17 Beta-Acetamide-4-Azasteroids As Androgen Receptor Modulators | MERCK SHARP & DOHME CORP. | 2008-05-29 | — | — | US | disclosed |
| US-7317029-B2 | 3,5-disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-20070112003-A1 | 3,5-disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use of thereof | CYTOVIA, INC. (US) | 2007-05-17 | — | — | US | disclosed |
| US-20070088028-A1 | 17-Acetamido-4-azasteroid derivatives as androgen receptor modulators | MERCK & CO., INC. | 2007-04-19 | — | — | US | disclosed |
| US-20060287349-A1 | 17-HETEROCYCLIC-4-AZASTEROID DERIVATIVES AS ANDROGEN RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. | 2006-12-21 | — | — | US | disclosed |
| US-7144876-B2 | 3,5-Disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2006-12-05 | — | — | US | disclosed |
| EP-1581213-A1 | 3,5-DISUBSTITUTED- 1,2,4 -OXADIAZOLES AND ANALOGS AS AC TIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | Cytovia, Inc. (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004058253-A1 | 3,5-DISUBSTITUTED-[1,2,4]-OXADIAZOLES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2004-07-15 | — | — | WO | disclosed |
| US-20040127521-A1 | 3,5-Disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127521-A1 | 3,5-Disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP1, CASP3, CASP2 | KDM4E 4071/4885ALDH1A1 155/4885POLB 2457/4885 |
| US-20230286918-A1 | MANUFACTURING PROCESS FOR 3,5-DICHLOROPICOLINONITRILE FOR SYNTHESIS OF VADADUSTAT | CYP3A4, CYP2D6, CYP2F1 | KDM4E 947/4885ALDH1A1 124/4885POLB 2919/4885 |
| US-20070112003-A1 | 3,5-disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use of thereof | CASP1, CASP3, CASP2 | KDM4E 3518/4885ALDH1A1 205/4885POLB 3297/4885 |
| US-20070088028-A1 | 17-Acetamido-4-azasteroid derivatives as androgen receptor modulators | AR, SHBG, NR5A1 | KDM4E 872/4885ALDH1A1 1619/4885POLB 1322/4885 |
| US-11827616-B2 | Heterocyclic compounds as pesticides | DDT, CHRM1, ACHE | KDM4E 1052/4885ALDH1A1 1236/4885POLB 4737/4885 |
| US-20060287349-A1 | 17-HETEROCYCLIC-4-AZASTEROID DERIVATIVES AS ANDROGEN RECEPTOR MODULATORS | AR, SHBG, NR5A1 | KDM4E 872/4885ALDH1A1 1800/4885POLB 1817/4885 |
| US-20240109860-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, CHRM1, ACHE | KDM4E 1052/4885ALDH1A1 1236/4885POLB 4737/4885 |
| US-20240059691-A1 | ENZYME INHIBITORS | SERPINB1, XDH, ACE | KDM4E 1708/4885ALDH1A1 627/4885POLB 424/4885 |
| US-20080125399-A1 | 17 Beta-Acetamide-4-Azasteroids As Androgen Receptor Modulators | AR, CYP17A1, SHBG | KDM4E 1067/4885ALDH1A1 967/4885POLB 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.