SCHEMBL12100676

SCHEMBL12100676

Cc1cccc(N2CN(C)c3nccnc32)c1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ADRB1 P08588 1/20 0.38
DHFR P00374 1/20 0.38
KCNH2 Q12809 2/20 0.38
GAA P10253 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12100620 0.84 GAA (0.39) ALDH1A1KDM4EMAPTHPGDL3MBTL1
SCHEMBL12100691 0.82 MAPT (0.38) ALDH1A1KDM4EMAPTL3MBTL1GAA
SCHEMBL16230044 0.81 ALDH1A1 (0.37) ALDH1A1KDM4EMAPTHPGDL3MBTL1
Iodide SCHEMBL30069231 0.80 MAPT (0.37) ALDH1A1KDM4EMAPTL3MBTL1GAA
SCHEMBL12100944 0.78 DHFR (0.41) ALDH1A1KDM4EMAPTHPGDL3MBTL1
SCHEMBL15576782 0.73 SMN1; SMN2 (0.38) ALDH1A1KDM4EMAPTHPGDGAA
SCHEMBL16545306 0.72 LMNA (0.44) ALDH1A1KDM4EMAPTTSHRNPSR1
SCHEMBL20201473 0.72 CYP3A4 (0.43) ALDH1A1MAPTL3MBTL1ADRB1GAA
SCHEMBL17754708 0.71 SMN1; SMN2 (0.40) ALDH1A1MAPTHPGDADRB1GAA
SCHEMBL26350318 0.71 GAA (0.40) ALDH1A1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11600791-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-03-07 US disclosed
EP-3936512-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS Universal Display Corporation (US) 2022-01-12 EP disclosed
EP-3424935-B1 IMIDAZOPYRAZINYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORP (US) 2021-08-11 EP disclosed
US-20210050530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
US-10873038-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-12-22 US disclosed
US-20190109287-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-04-11 US disclosed
EP-3424935-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS Universal Display Corporation (US) 2019-01-09 EP disclosed
EP-2683728-B1 IRIDIUM COMPLEXES WITH 3-PHENYL-3H-IMIDAZO[4,5-b]PYRIDINE, 3-PHENYL-3H-IMIDAZO[4,5-b]PYRAZINE AND 1-PHENYL-3H-IMIDAZO[4,5-b]PYRIDINE CARBENE LIGANDS USED AS PHOSPHORESCENT EMITTERS IN ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORP (US) 2018-09-05 EP disclosed
US-9972793-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-05-15 US disclosed
US-20150021590-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-01-22 US disclosed
US-20150021590-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-01-22 US disclosed
US-8883322-B2 Pyridyl carbene phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2014-11-11 US disclosed
EP-2683728-A2 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS Universal Display Corporation (US) 2014-01-15 EP disclosed
WO-2012121936-A2 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2012-09-13 WO disclosed
US-20120228583-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2012-09-13 US disclosed
WO-2012121936-A2 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2012-09-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210050530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NUDC, NCL, NDC1 ALDH1A1 3007/4885KDM4E 2183/4885MAPT 608/4885
US-10873038-B2 Organic electroluminescent materials and devices NUDC, NCL, NDC1 ALDH1A1 3007/4885KDM4E 2183/4885MAPT 608/4885
US-20120228583-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS PAICS, PIR, NUDC ALDH1A1 3390/4885KDM4E 2901/4885MAPT 672/4885
US-20190109287-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NUDC, NCL, NDC1 ALDH1A1 3007/4885KDM4E 2183/4885MAPT 608/4885
US-11600791-B2 Organic electroluminescent materials and devices NUDC, NCL, NDC1 ALDH1A1 3007/4885KDM4E 2183/4885MAPT 608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.