SCHEMBL12100620

SCHEMBL12100620

Cc1cccc(N2CN(C)c3cccnc32)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.39
DHFR P00374 1/20 0.39
KCNH2 Q12809 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
RXRA P19793 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2B Q13224 1/20 0.38
MAPT P10636 4/20 0.37
TSHR P16473 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 3/20 0.37
HPGD P15428 3/20 0.37
ALOX5 P09917 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
HSD17B10 Q99714 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15576782 0.91 SMN1; SMN2 (0.38) GAAMAPTALDH1A1KDM4EHPGD
SCHEMBL12100676 0.84 ALDH1A1 (0.40) GAADHFRKCNH2MEN1KMT2A
SCHEMBL12100565 0.83 DHFR (0.39) DHFRALDH1A1
SCHEMBL12100575 0.83 DRD2 (0.37) GAAMAPTALDH1A1KDM4EHPGD
SCHEMBL12100944 0.83 DHFR (0.41) GAADHFRKCNH2KMT2ARXRA
SCHEMBL16422195 0.78 GAA (0.31) GAAALDH1A1KDM4EHPGDSMN1; SMN2
SCHEMBL26350318 0.77 GAA (0.40) GAARXRAGRIN1GRIN2BMAPT
SCHEMBL20201470 0.77 GAA (0.46) GAAKMT2AMAPTTSHRNPSR1
SCHEMBL16728722 0.76 GAA (0.40) GAAMAPTNPSR1ALDH1A1HPGD
SCHEMBL26350341 0.74 MAPT (0.35) GAAKCNH2MEN1KMT2ARXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11600791-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-03-07 US disclosed
EP-3936512-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS Universal Display Corporation (US) 2022-01-12 EP disclosed
EP-3424935-B1 IMIDAZOPYRAZINYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORP (US) 2021-08-11 EP disclosed
EP-3424935-B1 IMIDAZOPYRAZINYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORP (US) 2021-08-11 EP disclosed
US-20210050530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
US-10873038-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-12-22 US disclosed
US-20190109287-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-04-11 US disclosed
EP-3424935-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS Universal Display Corporation (US) 2019-01-09 EP disclosed
EP-3424935-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS Universal Display Corporation (US) 2019-01-09 EP disclosed
EP-2683728-B1 IRIDIUM COMPLEXES WITH 3-PHENYL-3H-IMIDAZO[4,5-b]PYRIDINE, 3-PHENYL-3H-IMIDAZO[4,5-b]PYRAZINE AND 1-PHENYL-3H-IMIDAZO[4,5-b]PYRIDINE CARBENE LIGANDS USED AS PHOSPHORESCENT EMITTERS IN ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORP (US) 2018-09-05 EP disclosed
US-9972793-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-05-15 US disclosed
US-20150021590-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-01-22 US disclosed
US-8883322-B2 Pyridyl carbene phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2014-11-11 US disclosed
US-20120228583-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2012-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210050530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NUDC, NCL, NDC1 GAA 4009/4885DHFR 3444/4885KCNH2 82/4885
US-10873038-B2 Organic electroluminescent materials and devices NUDC, NCL, NDC1 GAA 4009/4885DHFR 3444/4885KCNH2 82/4885
US-20120228583-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS PAICS, PIR, NUDC GAA 4091/4885DHFR 2678/4885KCNH2 648/4885
US-20190109287-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NUDC, NCL, NDC1 GAA 4009/4885DHFR 3444/4885KCNH2 82/4885
US-11600791-B2 Organic electroluminescent materials and devices NUDC, NCL, NDC1 GAA 4009/4885DHFR 3444/4885KCNH2 82/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.