Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804382 | 0.92 | MEN1 (0.51) | MEN1KMT2AMAPK1DPP9DPP8 | |
| SCHEMBL12104313 | 0.89 | MEN1 (0.48) | MEN1KMT2AMAPK1DPP9DPP8 | |
| SCHEMBL12104073 | 0.81 | NPSR1 (0.45) | MEN1KMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL2221231 | 0.80 | MEN1 (0.52) | MEN1KMT2AMAPK1DPP9DPP8 | |
| SCHEMBL6225929 | 0.80 | GLA (0.46) | MEN1KMT2AEPHX2ALDH1A1RXFP1 | |
| SCHEMBL5802496 | 0.79 | MEN1 (0.51) | MEN1KMT2AMAPK1DPP9DPP8 | |
| SCHEMBL16259930 | 0.78 | MEN1 (0.52) | MEN1KMT2AMAPK1DPP9DPP8 | |
| SCHEMBL13287421 | 0.77 | MEN1 (0.55) | MEN1KMT2AMAPK1DPP9DPP8 | |
| SCHEMBL136224 | 0.76 | KMT2A (0.73) | MEN1KMT2AMAPK1DPP9DPP8 | |
| SCHEMBL15191498 | 0.76 | MEN1 (0.54) | MEN1KMT2AMAPK1DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309597-B2 | 1,1′-diadamantyl carboxylic acids, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-11-13 | — | — | US | disclosed |
| US-20110269736-A1 | 1,1'-Diadamantyl carboxylic acids, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269736-A1 | 1,1'-Diadamantyl carboxylic acids, medicaments containing such compounds and their use | HSD11B1, HSD17B1, HSD3B1 | MEN1 1772/4885KMT2A 3062/4885MAPK1 890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.