Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13224505 | 0.82 | MAPT (0.89) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL21324338 | 0.80 | MAPT (0.60) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL12109355 | 0.80 | MAPT (0.60) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL12109299 | 0.77 | MAPT (0.57) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL12109319 | 0.77 | MAPT (0.81) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL31914 | 0.77 | MAPT (1.00) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL19065779 | 0.77 | MAPT (0.79) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL16892742 | 0.76 | MAPT (0.56) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL28658698 | 0.76 | MAPT (0.78) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL8025393 | 0.75 | MAPT (0.71) | MAPTALOX15KDM4EPOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110266533-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110266533-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | SLCO2A1, SLC40A1, TOE1 | MAPT 1198/4885ALOX15 874/4885KDM4E 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.