Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 11/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12111241 | 0.90 | MRGPRX4 (0.48) | PPARAMRGPRX4FFAR4PTGER1 | |
| SCHEMBL12112567 | 0.90 | TSHR (0.46) | PTPN2PTPN1PTPN6 | |
| SCHEMBL12797286 | 0.82 | KDM4E (0.52) | PPARDMRGPRX4FFAR4CTSSRXRA | |
| SCHEMBL12797522 | 0.80 | PPARD (0.46) | PPARDPPARAMRGPRX4FFAR4CTSS | |
| SCHEMBL12797607 | 0.80 | HRH3 (0.47) | PPARDMRGPRX4FFAR4CTSSRXRA | |
| SCHEMBL12112554 | 0.79 | TSHR (0.49) | — | |
| SCHEMBL12797392 | 0.78 | NPC1 (0.61) | PPARDMRGPRX4FFAR4CTSS | |
| SCHEMBL18703359 | 0.78 | MRGPRX4 (0.61) | PPARDMRGPRX4FFAR4RXRARXRB | |
| SCHEMBL12111298 | 0.75 | PPARD (0.45) | PPARDPPARAMRGPRX4FFAR4PTPN2 | |
| SCHEMBL12797212 | 0.73 | HRH3 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329739-B2 | Phenylimidazole compounds | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20110275823-A1 | PHENYLIMIDAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275823-A1 | PHENYLIMIDAZOLE COMPOUNDS | GPR119, PNLIP, LPL | PPARD 75/4885PPARA 66/4885MRGPRX4 1665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.