SCHEMBL12113166

SCHEMBL12113166

Cc1cc(Cl)cc(C(=O)NC(C)C)c1NC(=O)c1cc(Cn2ccnn2)nn1-c1ncccc1Cl

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
F10 P00742 3/20 0.37
F9 P00740 1/20 0.37
DHODH Q02127 2/20 0.34
CAPN1 P07384 1/20 0.33
NTRK1 P04629 4/20 0.32
MALT1 Q9UDY8 1/20 0.32
EIF2S1 P05198 3/20 0.32
EIF2AK3 Q9NZJ5 3/20 0.32
ROCK2 O75116 1/20 0.32
CNR1 P21554 2/20 0.32
CNR2 P34972 1/20 0.32
F2 P00734 1/20 0.32
GPR88 Q9GZN0 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12113170 0.92 F9 (0.36) F10F9DHODHMALT1CNR1
SCHEMBL12113172 0.88 CAPN1 (0.34) F10DHODHCAPN1MALT1EIF2S1
SCHEMBL16181542 0.87 MALT1 (0.35) DHODHCAPN1NTRK1MALT1EIF2S1
SCHEMBL15255583 0.86 SLC2A1 (0.34) DHODHCAPN1NTRK1MALT1
SCHEMBL12113409 0.86 DHODH (0.34) DHODHCAPN1NTRK1MALT1
SCHEMBL12117039 0.85 DHODH (0.33) DHODH
SCHEMBL13085332 0.85 DHODH (0.33) DHODHCAPN1MALT1EIF2S1EIF2AK3
SCHEMBL782483 0.85 MALT1 (0.37) F10DHODHCAPN1MALT1EIF2S1
SCHEMBL12936147 0.85 KMT2A (0.38) F10DHODHNTRK1MALT1CNR1
SCHEMBL12113487 0.84 DHODH (0.34) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8536202-B2 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2013-09-17 US disclosed
US-8536202-B2 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2013-09-17 US disclosed
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2011-11-10 US disclosed
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2011-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides AADAC, NAAA, ANTXR2 F10 1433/4885F9 1273/4885DHODH 3052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.