SCHEMBL782483

SCHEMBL782483

Cc1cc(Cl)cc(C(=O)NC(C)C)c1NC(=O)c1cc(Cl)nn1-c1ncccc1Cl

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 4/20 0.37
RECQL P46063 1/20 0.36
DHODH Q02127 1/20 0.36
CNR1 P21554 2/20 0.35
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
CNR2 P34972 1/20 0.35
EIF2S1 P05198 1/20 0.34
EIF2AK3 Q9NZJ5 1/20 0.34
PDE4A P27815 3/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34
CAPN1 P07384 1/20 0.34
F10 P00742 1/20 0.34
LMNA P02545 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10140185 0.94 RECQL (0.36) MALT1RECQLCNR1ALDH1A1POLB
SCHEMBL16622533 0.93 MALT1 (0.36) MALT1DHODHF10KMT2AKCNH2
SCHEMBL12936147 0.93 KMT2A (0.38) MALT1RECQLDHODHCNR1MAPT
SCHEMBL782499 0.93 CNR1 (0.36) MALT1RECQLDHODHCNR1ALDH1A1
SCHEMBL14435048 0.92 PDE4A (0.35) MALT1RECQLDHODHCNR1ALDH1A1
SCHEMBL13242831 0.91 DHODH (0.35) MALT1DHODHCNR1ALDH1A1POLB
SCHEMBL16502008 0.91 PDE4B (0.37) MALT1RECQLDHODHCNR1ALDH1A1
SCHEMBL782462 0.91 DHODH (0.38) MALT1DHODHCNR1ALDH1A1POLB
SCHEMBL782232 0.91 DHODH (0.43) MALT1RECQLDHODHCNR1ALDH1A1
SCHEMBL7163318 0.91 MALT1 (0.35) MALT1DHODHPDE4APDE4DF10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2910125-B1 INSECTICIDE COMPOSITIONS SUMITOMO CHEMICAL CO (JP) 2018-05-02 EP claimed
US-20160270396-A1 INSECTICIDE COMPOSITIONS SUMITOMO CHEMICAL CO (JP) 2016-09-22 US claimed
US-9408390-B2 Insecticide compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US claimed
US-20150282484-A1 INSECTICIDE COMPOSITIONS SUMITOMO CHEMICAL CO (JP) 2015-10-08 US claimed
EP-2910125-A1 Insecticide compositions Sumitomo Chemical Company, Limited (JP) 2015-08-26 EP claimed
US-9095137-B2 Insecticide compositions SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2015-08-04 US claimed
EP-2474227-B1 Insecticide compositions SUMITOMO CHEMICAL CO (JP) 2015-04-15 EP claimed
EP-2484209-B1 Insecticide compositions SUMITOMO CHEMICAL CO (JP) 2015-04-01 EP claimed
EP-2484209-A1 Insecticide compositions Sumitomo Chemical Company, Limited (JP) 2012-08-08 EP claimed
EP-2474227-A1 Insecticide compositions Sumitomo Chemical Co., Ltd (JP) 2012-07-11 EP claimed
EP-1719409-B1 INSECTICIDE COMPOSITION SUMITOMO CHEMICAL CO (JP) 2012-07-11 EP claimed
US-20100227893-A1 INSECTICIDE COMPOSITIONS OHKAWARA YUICHI 2010-09-09 US claimed
US-20070259787-A1 Insecticide Compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-11-08 US claimed
EP-1719409-A1 INSECTICIDE COMPOSITION Sumitomo Chemical Takeda Agro Company, Limited (JP) 2006-11-08 EP claimed
US-20210378242-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, LLC (US) 2021-12-09 US disclosed
US-10405548-B2 Fungicidal compositions SYNGENTA CROP PROTECTION LLC (US) 2019-09-10 US disclosed
EP-2547665-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-07-04 EP disclosed
US-20040198984-A1 1-(3-halopyrid-2-yl)-3-substituted-5-((2,4-substituted-6-aminocarbonyl)phenylaminocarbonyl) pyrazoles insecticides FMC CORPORATION 2004-10-07 US disclosed
EP-1416797-A1 ARTHROPODICIDAL ANTHRANILAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-05-12 EP disclosed
WO-2003015519-A1 ARTHROPODICIDAL ANTHRANILAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210378242-A1 FUNGICIDAL COMPOSITIONS PIK3C3, CYP51A1, CYP1B1 MALT1 1035/4885RECQL 2911/4885DHODH 874/4885
US-20100227893-A1 INSECTICIDE COMPOSITIONS DDT, NISCH, ITPR3 MALT1 4735/4885RECQL 2633/4885DHODH 830/4885
US-20070259787-A1 Insecticide Compositions DDT, NISCH, ITPR3 MALT1 4735/4885RECQL 2633/4885DHODH 830/4885
US-20040198984-A1 1-(3-halopyrid-2-yl)-3-substituted-5-((2,4-substituted-6-aminocarbonyl)phenylaminocarbonyl) pyrazoles insecticides CYP4B1, CYP1B1, CYP2E1 MALT1 3253/4885RECQL 1320/4885DHODH 2558/4885
US-10405548-B2 Fungicidal compositions PIK3C3, CYP51A1, CYP1B1 MALT1 1035/4885RECQL 2911/4885DHODH 874/4885
US-20160270396-A1 INSECTICIDE COMPOSITIONS DDT, NISCH, ITPR3 MALT1 4735/4885RECQL 2633/4885DHODH 830/4885
US-20150282484-A1 INSECTICIDE COMPOSITIONS DDT, NISCH, ITPR3 MALT1 4735/4885RECQL 2633/4885DHODH 830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.