Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 2/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 6/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770819 | 1.00 | CHAT (0.61) | CHATALDH1A1KDM4EHPGDCYP2C19 | |
| Iodide SCHEMBL31042224 | 0.98 | ALDH1A1 (0.64) | CHATALDH1A1KDM4EHPGDCYP2C19 | |
| SCHEMBL30612471 | 0.88 | CHAT (0.76) | CHATALDH1A1KDM4EHPGDCYP2C19 | |
| SCHEMBL10001242 | 0.85 | CHAT (0.80) | CHATALDH1A1KDM4EHPGDCYP2C19 | |
| SCHEMBL12519753 | 0.85 | CHAT (0.80) | CHATALDH1A1KDM4EHPGDCYP2C19 | |
| SCHEMBL13964870 | 0.83 | ALDH1A1 (0.70) | CHATALDH1A1KDM4EHPGDCYP2C19 | |
| Iodide SCHEMBL1804181 | 0.82 | ALDH1A1 (0.68) | CHATALDH1A1KDM4EHPGDCYP2C19 | |
| Iodide SCHEMBL1804188 | 0.82 | ALDH1A1 (0.68) | CHATALDH1A1KDM4EHPGDCYP2C19 | |
| SCHEMBL6266987 | 0.80 | APP (0.74) | ALDH1A1KDM4EHPGDCYP2C19RAB9A | |
| SCHEMBL9678787 | 0.80 | APP (0.74) | ALDH1A1KDM4EHPGDCYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151602-A1 | DETACHABLE MICRONEEDLE ARRAYS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2024-07-18 | — | — | WO | disclosed |
| US-8835632-B2 | Methods to increase the photostability of dyes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-09-16 | — | — | US | disclosed |
| US-8349222-B2 | Twisted π-electron system chromophore compounds with very large molecular hyperpolarizabilities and related compositions and devices | NORTHWESTERN UNIVERSITY (US) | 2013-01-08 | — | — | US | disclosed |
| US-20120294808-A1 | Fluorescent Analogs of Neurotransmitters, Compositions Containing the Same and Methods of Using the Same | UNIVERSITY OF MIAMI (US) | 2012-11-22 | — | — | US | disclosed |
| US-20120294808-A1 | Fluorescent Analogs of Neurotransmitters, Compositions Containing the Same and Methods of Using the Same | UNIVERSITY OF MIAMI (US) | 2012-11-22 | — | — | US | disclosed |
| US-20110278512-A1 | Twisted Pi-Electron System Chromophore Compounds with Very Large Molecular Hyperpolarizabilities and Related Compositions and Devices | Northwestem University (US) | 2011-11-17 | — | — | US | disclosed |
| US-7968016-B2 | Twisted π-electron system chromophore compounds with very large molecular hyperpolarizabilities and related compositions and devices | NORTHWESTERN UNIVERSITY (US) | 2011-06-28 | — | — | US | disclosed |
| US-20110046000-A1 | METHODS TO INCREASE THE PHOTOSTABILITY OF DYES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-02-24 | — | — | US | disclosed |
| US-7824582-B2 | Twisted π-electron system chromophore compounds with very large molecular hyperpolarizabilities and related compositions and devices | NORTHWESTERN UNIVERSITY (US) | 2010-11-02 | — | — | US | disclosed |
| US-7824582-B2 | Twisted π-electron system chromophore compounds with very large molecular hyperpolarizabilities and related compositions and devices | NORTHWESTERN UNIVERSITY (US) | 2010-11-02 | — | — | US | disclosed |
| US-20100273919-A1 | TWISTED PI-ELECTRON SYSTEM CHROMOPHORE COMPOUNDS WITH VERY LARGE MOLECULAR HYPERPOLARIZABILITIES AND RELATED COMPOSITIONS AND DEVICES | NATIONAL SCIENCE FOUNDATION | 2010-10-28 | — | — | US | disclosed |
| EP-1161555-B1 | 4-(4-HYDROXYSTYRYL)PYRIDINE-CONTAINING SUBSTRATES FOR AN ANALYTE DEPENDENT ENZYME ACTIVATION SYSTEM | PERKINELMER LAS INC (US) | 2008-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120294808-A1 | Fluorescent Analogs of Neurotransmitters, Compositions Containing the Same and Methods of Using the Same | HRH3, CHRNA4, HRH4 | CHAT 42/4885ALDH1A1 1735/4885KDM4E 2970/4885 |
| US-20110046000-A1 | METHODS TO INCREASE THE PHOTOSTABILITY OF DYES | PTMS, ACP1, SNRPE | CHAT 2928/4885ALDH1A1 3978/4885KDM4E 3420/4885 |
| US-20100273919-A1 | TWISTED PI-ELECTRON SYSTEM CHROMOPHORE COMPOUNDS WITH VERY LARGE MOLECULAR HYPERPOLARIZABILITIES AND RELATED COMPOSITIONS AND DEVICES | PAX3, OPA1, LAGE3 | CHAT 694/4885ALDH1A1 4309/4885KDM4E 3843/4885 |
| US-20110278512-A1 | Twisted Pi-Electron System Chromophore Compounds with Very Large Molecular Hyperpolarizabilities and Related Compositions and Devices | PAX3, OPA1, LAGE3 | CHAT 694/4885ALDH1A1 4309/4885KDM4E 3843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.